Pth GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Pth
parathyroid hormone
MGI:97799

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005179	hormone activity	ISO	J:155856
Molecular Function	GO:0005179	hormone activity	ISO	J:164563
Molecular Function	GO:0005179	hormone activity	IBA	J:265628
Molecular Function	GO:0005179	hormone activity	IDA	J:95384
Molecular Function	GO:0005179	hormone activity	IDA	J:72784
Molecular Function	GO:0005179	hormone activity	IDA	J:95384
Molecular Function	GO:0031856	parathyroid hormone receptor binding	ISO	J:155856
Molecular Function	GO:0031856	parathyroid hormone receptor binding	IBA	J:265628
Molecular Function	GO:0051428	peptide hormone receptor binding	ISO	J:155856
Molecular Function	GO:0051428	peptide hormone receptor binding	ISO	J:164563
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:155856
Molecular Function	GO:0031857	type 1 parathyroid hormone receptor binding	ISO	J:155856
Molecular Function	GO:0031857	type 1 parathyroid hormone receptor binding	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:72784
Cellular Component	GO:0005615	extracellular space	IDA	J:206158
Biological Process	GO:0007202	activation of phospholipase C activity	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:37692
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:73065
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	J:152384
Biological Process	GO:0030282	bone mineralization	IMP	J:233135
Biological Process	GO:0030282	bone mineralization	IMP	J:233135
Biological Process	GO:0055074	calcium ion homeostasis	IMP	J:233135
Biological Process	GO:0055074	calcium ion homeostasis	IMP	J:233135
Biological Process	GO:0007267	cell-cell signaling	ISO	J:155856
Biological Process	GO:0007267	cell-cell signaling	IBA	J:265628
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IGI	J:166692
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:155856
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IDA	J:80827
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:73065
Biological Process	GO:0009059	macromolecule biosynthetic process	ISO	J:152384
Biological Process	GO:0010960	magnesium ion homeostasis	IMP	J:233135
Biological Process	GO:0010960	magnesium ion homeostasis	IMP	J:233135
Biological Process	GO:0071866	negative regulation of apoptotic process in bone marrow cell	IGI	J:166692
Biological Process	GO:1900158	negative regulation of bone mineralization involved in bone maturation	ISO	J:155856
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0055062	phosphate ion homeostasis	IMP	J:233135
Biological Process	GO:0055062	phosphate ion homeostasis	IMP	J:233135
Biological Process	GO:0030501	positive regulation of bone mineralization	ISO	J:164563
Biological Process	GO:0030501	positive regulation of bone mineralization	ISO	J:155856
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	IGI	J:166692
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	IGI	J:166692
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0046326	positive regulation of glucose import	ISO	J:164563
Biological Process	GO:0045725	positive regulation of glycogen biosynthetic process	ISO	J:164563
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	ISO	J:164563
Biological Process	GO:0045778	positive regulation of ossification	ISO	J:155856
Biological Process	GO:0090290	positive regulation of osteoclast proliferation	IGI	J:166692
Biological Process	GO:0009967	positive regulation of signal transduction	IMP	J:98600
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:152384
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:98600
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0010468	regulation of gene expression	ISO	J:37692
Biological Process	GO:0010468	regulation of gene expression	IDA	J:98600
Biological Process	GO:0007266	Rho protein signal transduction	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IMP	J:98600
Biological Process	GO:0007165	signal transduction	IMP	J:98600
Biological Process	GO:0007165	signal transduction	IMP	J:98600
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:98600
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:98600
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:98600

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23