GO Annotations Graph

• Symbol: Plau
• Name: plasminogen activator, urokinase
• ID: MGI:97611

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:230206
Molecular Function	GO:0004252	serine-type endopeptidase activity	IBA	J:265628
Molecular Function	GO:0008236	serine-type peptidase activity	IEA	J:72247
Molecular Function	GO:0008236	serine-type peptidase activity	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0098637	protein complex involved in cell-matrix adhesion	ISO	J:164563
Cellular Component	GO:0097180	serine protease inhibitor complex	ISO	J:164563
Cellular Component	GO:1905370	serine-type endopeptidase complex	ISO	J:164563
Cellular Component	GO:1905370	serine-type endopeptidase complex	IPI	J:165944
Biological Process	GO:0001525	angiogenesis	ISO	J:155856
Biological Process	GO:0042730	fibrinolysis	IBA	J:265628
Biological Process	GO:0042730	fibrinolysis	IMP	J:49265
Biological Process	GO:0051918	negative regulation of fibrinolysis	NAS	J:320118
Biological Process	GO:0010757	negative regulation of plasminogen activation	NAS	J:320118
Biological Process	GO:0070997	neuron death	ISO	J:155856
Biological Process	GO:0031639	plasminogen activation	ISO	J:164563
Biological Process	GO:0031639	plasminogen activation	IBA	J:265628
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:230206
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0060279	positive regulation of ovulation	ISO	J:155856
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	ISO	J:155856
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0006508	proteolysis	IEA	J:72247
Biological Process	GO:0030155	regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	IBA	J:265628
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:126931
Biological Process	GO:0051917	regulation of fibrinolysis	NAS	J:320117
Biological Process	GO:2000345	regulation of hepatocyte proliferation	ISO	J:155856
Biological Process	GO:0010755	regulation of plasminogen activation	NAS	J:320117
Biological Process	GO:0010469	regulation of signaling receptor activity	ISO	J:164563
Biological Process	GO:0014910	regulation of smooth muscle cell migration	ISO	J:164563
Biological Process	GO:2000097	regulation of smooth muscle cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0001666	response to hypoxia	IMP	J:124454
Biological Process	GO:0043403	skeletal muscle tissue regeneration	ISO	J:155856
Biological Process	GO:0014909	smooth muscle cell migration	IMP	J:124454
Biological Process	GO:0038195	urokinase plasminogen activator signaling pathway	NAS	J:320117
Biological Process	GO:0042060	wound healing	ISO	J:155856