GO Annotations Graph

• Symbol: Pkd1
• Name: polycystin 1, transient receptor potential channel interacting
• ID: MGI:97603

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IMP	J:81443
Molecular Function	GO:0005262	calcium channel activity	ISO	J:164563
Molecular Function	GO:0005262	calcium channel activity	TAS	J:76062
Molecular Function	GO:0030246	carbohydrate binding	IEA	J:60000
Molecular Function	GO:0005261	monoatomic cation channel activity	IPI	J:96951
Molecular Function	GO:0005515	protein binding	IPI	J:274079
Molecular Function	GO:0005515	protein binding	IPI	J:187613
Molecular Function	GO:0005515	protein binding	IPI	J:245263
Molecular Function	GO:0005515	protein binding	IPI	J:76062
Molecular Function	GO:0005515	protein binding	IPI	J:96951
Molecular Function	GO:0005515	protein binding	IPI	J:77086
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0042813	Wnt receptor activity	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0034704	calcium channel complex	ISO	J:164563
Cellular Component	GO:0034703	cation channel complex	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	IDA	J:214729
Cellular Component	GO:0005929	cilium	IDA	J:274079
Cellular Component	GO:0005929	cilium	IDA	J:214729
Cellular Component	GO:0005929	cilium	IDA	J:148449
Cellular Component	GO:0005929	cilium	ISO	J:246963
Cellular Component	GO:0005929	cilium	IDA	J:81443
Cellular Component	GO:0005737	cytoplasm	IMP	J:182496
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:274079
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:274079
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0031514	motile cilium	IDA	J:99441
Cellular Component	GO:0031514	motile cilium	IDA	J:99441
Cellular Component	GO:0005634	nucleus	IDA	J:94419
Cellular Component	GO:0005634	nucleus	IDA	J:94419
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:73065
Cellular Component	GO:0005886	plasma membrane	IPI	J:96951
Cellular Component	GO:0002133	polycystin complex	IDA	J:274079
Cellular Component	GO:0002133	polycystin complex	ISO	J:164563
Cellular Component	GO:0002133	polycystin complex	IPI	J:77086
Cellular Component	GO:0002133	polycystin complex	IDA	J:77086
Biological Process	GO:0001568	blood vessel development	IMP	J:68331
Biological Process	GO:0060854	branching involved in lymph vessel morphogenesis	ISO	J:73065
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	ISO	J:164563
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	IDA	J:214729
Biological Process	GO:0070588	calcium ion transmembrane transport	IMP	J:81443
Biological Process	GO:0006816	calcium ion transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	IDA	J:81443
Biological Process	GO:0006816	calcium ion transport	IBA	J:265628
Biological Process	GO:0006816	calcium ion transport	IMP	J:81443
Biological Process	GO:0001502	cartilage condensation	IMP	J:72238
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:68331
Biological Process	GO:0198738	cell-cell signaling by wnt	ISO	J:164563
Biological Process	GO:0042994	cytoplasmic sequestering of transcription factor	IMP	J:182496
Biological Process	GO:0050982	detection of mechanical stimulus	IDA	J:94419
Biological Process	GO:0050982	detection of mechanical stimulus	IMP	J:81443
Biological Process	GO:0001892	embryonic placenta development	IMP	J:165114
Biological Process	GO:0090162	establishment of epithelial cell polarity	IMP	J:211805
Biological Process	GO:0007507	heart development	IMP	J:72238
Biological Process	GO:0007507	heart development	IMP	J:222159
Biological Process	GO:0001701	in utero embryonic development	IGI	J:126158
Biological Process	GO:0001701	in utero embryonic development	IMP	J:126158
Biological Process	GO:0001822	kidney development	IMP	J:165114
Biological Process	GO:0001822	kidney development	IGI	J:188763
Biological Process	GO:0001822	kidney development	IMP	J:231949
Biological Process	GO:0001822	kidney development	IMP	J:173488
Biological Process	GO:0001889	liver development	IGI	J:188763
Biological Process	GO:0036303	lymph vessel morphogenesis	IMP	J:211805
Biological Process	GO:0006807	nitrogen compound metabolic process	IGI	J:188763
Biological Process	GO:0006807	nitrogen compound metabolic process	IGI	J:188763
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IMP	J:158762
Biological Process	GO:0060674	placenta blood vessel development	IMP	J:165114
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0032092	positive regulation of protein binding	IMP	J:182496
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006611	protein export from nucleus	IMP	J:158762
Biological Process	GO:0051290	protein heterotetramerization	ISO	J:164563
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	EXP	J:76062
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	IDA	J:76062
Biological Process	GO:0030155	regulation of cell adhesion	IMP	J:211805
Biological Process	GO:0051726	regulation of cell cycle	IDA	J:76062
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0060236	regulation of mitotic spindle organization	IMP	J:188763
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	IMP	J:191148
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	ISO	J:73065
Biological Process	GO:0034405	response to fluid shear stress	IMP	J:148449
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000