GO Annotations Graph

• Symbol: Pam
• Name: peptidylglycine alpha-amidating monooxygenase
• ID: MGI:97475

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:155856
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0005507	copper ion binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0031418	L-ascorbic acid binding	IEA	J:60000
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen	IEA	J:72247
Molecular Function	GO:0004598	peptidylamidoglycolate lyase activity	ISO	J:164563
Molecular Function	GO:0004598	peptidylamidoglycolate lyase activity	ISO	J:155856
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	ISO	J:164563
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	ISO	J:155856
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	IBA	J:265628
Molecular Function	GO:0004504	peptidylglycine monooxygenase activity	TAS	J:54990
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	J:54990
Cellular Component	GO:0005576	extracellular region	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	J:54990
Cellular Component	GO:0030141	secretory granule	ISO	J:155856
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:155856
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:155856
Biological Process	GO:0062112	fatty acid primary amide biosynthetic process	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0001519	peptide amidation	ISO	J:164563
Biological Process	GO:0001519	peptide amidation	ISO	J:155856
Biological Process	GO:0006518	peptide metabolic process	ISO	J:155856
Biological Process	GO:0006518	peptide metabolic process	TAS	J:54990
Biological Process	GO:0018032	protein amidation	ISO	J:155856
Biological Process	GO:0019538	protein metabolic process	ISO	J:155856
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:155856
Biological Process	GO:0050708	regulation of protein secretion	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0009268	response to pH	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0010043	response to zinc ion	ISO	J:164563
Biological Process	GO:0009404	toxin metabolic process	ISO	J:155856