Ntrk1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
MGI:97383

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0019900	kinase binding	ISO	J:155856
Molecular Function	GO:0048406	nerve growth factor binding	ISO	J:155856
Molecular Function	GO:0048406	nerve growth factor binding	ISO	J:164563
Molecular Function	GO:0010465	nerve growth factor receptor activity	ISO	J:164563
Molecular Function	GO:0043121	neurotrophin binding	IBA	J:265628
Molecular Function	GO:0005166	neurotrophin p75 receptor binding	ISO	J:155856
Molecular Function	GO:0005030	neurotrophin receptor activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:231844
Molecular Function	GO:0005515	protein binding	IPI	J:154926
Molecular Function	GO:0005515	protein binding	IPI	J:100024
Molecular Function	GO:0005515	protein binding	IPI	J:120306
Molecular Function	GO:0005515	protein binding	IPI	J:100024
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:207835
Molecular Function	GO:0005515	protein binding	IPI	J:100024
Molecular Function	GO:0005515	protein binding	IPI	J:145554
Molecular Function	GO:0005515	protein binding	IPI	J:100024
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:145554
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	ISO	J:237361
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:207835
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:145554
Cellular Component	GO:0009986	cell surface	IDA	J:210609
Cellular Component	GO:0005737	cytoplasm	IDA	J:71586
Cellular Component	GO:0005737	cytoplasm	IDA	J:54178
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0005769	early endosome	IDA	J:210609
Cellular Component	GO:0005769	early endosome	IDA	J:207835
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005770	late endosome	ISO	J:155856
Cellular Component	GO:0005770	late endosome	IDA	J:210609
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-198263
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-198275
Cellular Component	GO:0005886	plasma membrane	ISO	J:237361
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0055037	recycling endosome	ISO	J:155856
Biological Process	GO:0007411	axon guidance	ISO	J:155856
Biological Process	GO:0060385	axonogenesis involved in innervation	IMP	J:35563
Biological Process	GO:0030183	B cell differentiation	IMP	J:93578
Biological Process	GO:0061368	behavioral response to formalin induced pain	IMP	J:210609
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071363	cellular response to growth factor stimulus	ISO	J:145554
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	ISO	J:155856
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	ISO	J:164563
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	IBA	J:265628
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	IDA	J:210609
Biological Process	GO:0071316	cellular response to nicotine	ISO	J:155856
Biological Process	GO:0007623	circadian rhythm	IEP	J:199564
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	ISO	J:155856
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	ISO	J:155856
Biological Process	GO:0060384	innervation	IMP	J:210609
Biological Process	GO:0007611	learning or memory	ISO	J:155856
Biological Process	GO:0042490	mechanoreceptor differentiation	IMP	J:93853
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:35563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:72722
Biological Process	GO:1901215	negative regulation of neuron death	ISO	J:155856
Biological Process	GO:0038180	nerve growth factor signaling pathway	ISO	J:164563
Biological Process	GO:0038180	nerve growth factor signaling pathway	ISO	J:155856
Biological Process	GO:0038180	nerve growth factor signaling pathway	IBA	J:265628
Biological Process	GO:0038180	nerve growth factor signaling pathway	IGI	J:207835
Biological Process	GO:0038180	nerve growth factor signaling pathway	IDA	J:21389
Biological Process	GO:0038180	nerve growth factor signaling pathway	IGI	J:207835
Biological Process	GO:0007399	nervous system development	IDA	J:83805
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:72722
Biological Process	GO:0048666	neuron development	ISO	J:237361
Biological Process	GO:0031175	neuron projection development	ISO	J:237361
Biological Process	GO:0048011	neurotrophin TRK receptor signaling pathway	ISO	J:164563
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	ISO	J:164563
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	ISO	J:237361
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	IBA	J:265628
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IBA	J:265628
Biological Process	GO:0043068	positive regulation of programmed cell death	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	ISO	J:164563
Biological Process	GO:0051965	positive regulation of synapse assembly	IDA	J:211830
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0010623	programmed cell death involved in cell development	ISO	J:155856
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:145554
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:76516
Biological Process	GO:0051896	regulation of protein kinase B signaling	IBA	J:265628
Biological Process	GO:0014823	response to activity	ISO	J:155856
Biological Process	GO:0051602	response to electrical stimulus	ISO	J:155856
Biological Process	GO:0035094	response to nicotine	ISO	J:155856
Biological Process	GO:0031667	response to nutrient levels	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0060009	Sertoli cell development	ISO	J:155856
Biological Process	GO:0048485	sympathetic nervous system development	IMP	J:35563
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23