GO Annotations Graph

• Symbol: Nfe2
• Name: nuclear factor, erythroid derived 2
• ID: MGI:97308

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:160776
Molecular Function	GO:0005515	protein binding	IPI	J:153740
Molecular Function	GO:0005515	protein binding	IPI	J:173620
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0050699	WW domain binding	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-1008243
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:22119
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Biological Process	GO:0030282	bone mineralization	IMP	J:111270
Biological Process	GO:0008283	cell population proliferation	IDA	J:125982
Biological Process	GO:0007267	cell-cell signaling	IMP	J:111270
Biological Process	GO:0010467	gene expression	IMP	J:246556
Biological Process	GO:0010467	gene expression	IDA	J:246556
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:173620
Biological Process	GO:0030502	negative regulation of bone mineralization	IMP	J:111270
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:125982
Biological Process	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion	IGI	J:173620
Biological Process	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion	IMP	J:173620
Biological Process	GO:2000758	positive regulation of peptidyl-lysine acetylation	IMP	J:173620
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IDA	J:125982
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000768	syncytium formation by plasma membrane fusion	IGI	J:173620
Biological Process	GO:0000768	syncytium formation by plasma membrane fusion	IMP	J:173620