GO Annotations Graph

• Symbol: Myod1
• Name: myogenic differentiation 1
• ID: MGI:97275

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	IPI	J:48121
Molecular Function	GO:0003682	chromatin binding	IDA	J:230626
Molecular Function	GO:0003682	chromatin binding	IDA	J:206594
Molecular Function	GO:0003682	chromatin binding	IDA	J:142475
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:216211
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:145753
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:82185
Molecular Function	GO:0003677	DNA binding	IDA	J:48121
Molecular Function	GO:0001216	DNA-binding transcription activator activity	IDA	J:200312
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:69575
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:99106
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:99106
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:209066
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:99106
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:228418
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:228292
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:228292
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:82185
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	TAS	J:27708
Molecular Function	GO:0070888	E-box binding	IDA	J:200312
Molecular Function	GO:0070888	E-box binding	ISO	J:155856
Molecular Function	GO:0070888	E-box binding	IDA	J:69575
Molecular Function	GO:0019899	enzyme binding	IPI	J:165849
Molecular Function	GO:0016922	nuclear receptor binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:259135
Molecular Function	GO:0005515	protein binding	IPI	J:228418
Molecular Function	GO:0005515	protein binding	IPI	J:192072
Molecular Function	GO:0005515	protein binding	IPI	J:149882
Molecular Function	GO:0005515	protein binding	IPI	J:182387
Molecular Function	GO:0005515	protein binding	IPI	J:238468
Molecular Function	GO:0005515	protein binding	IPI	J:180159
Molecular Function	GO:0005515	protein binding	IPI	J:204624
Molecular Function	GO:0005515	protein binding	IPI	J:200435
Molecular Function	GO:0005515	protein binding	IPI	J:306710
Molecular Function	GO:0005515	protein binding	IPI	J:95029
Molecular Function	GO:0005515	protein binding	IPI	J:153063
Molecular Function	GO:0005515	protein binding	IPI	J:214868
Molecular Function	GO:0005515	protein binding	IPI	J:165945
Molecular Function	GO:0005515	protein binding	IPI	J:180463
Molecular Function	GO:0005515	protein binding	IPI	J:177741
Molecular Function	GO:0005515	protein binding	IPI	J:180463
Molecular Function	GO:0005515	protein binding	IPI	J:72619
Molecular Function	GO:0005515	protein binding	IPI	J:38665
Molecular Function	GO:0005515	protein binding	IPI	J:165945
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:69575
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:73523
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:69575
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:217579
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:198757
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0008134	transcription factor binding	IPI	J:198757
Molecular Function	GO:0008134	transcription factor binding	IPI	J:206594
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:147457
Cellular Component	GO:0000785	chromatin	IDA	J:165849
Cellular Component	GO:0005737	cytoplasm	IDA	J:147457
Cellular Component	GO:0000791	euchromatin	IDA	J:69575
Cellular Component	GO:0030016	myofibril	IDA	J:147457
Cellular Component	GO:0030016	myofibril	IDA	J:168699
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-448949
Cellular Component	GO:0005634	nucleus	IDA	J:243401
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:180556
Cellular Component	GO:0005634	nucleus	IDA	J:228292
Cellular Component	GO:0005634	nucleus	IDA	J:181629
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	IDA	J:84672
Cellular Component	GO:0005634	nucleus	IDA	J:181629
Cellular Component	GO:0005634	nucleus	IDA	J:72619
Cellular Component	GO:0005634	nucleus	TAS	J:27708
Cellular Component	GO:0005634	nucleus	IDA	J:147457
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:48121
Biological Process	GO:0055007	cardiac muscle cell differentiation	NAS	J:173154
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071392	cellular response to estradiol stimulus	IDA	J:200312
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	IDA	J:147457
Biological Process	GO:0071453	cellular response to oxygen levels	IDA	J:147457
Biological Process	GO:0009267	cellular response to starvation	IDA	J:147457
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IDA	J:211147
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0042692	muscle cell differentiation	IDA	J:200312
Biological Process	GO:0007517	muscle organ development	IDA	J:91568
Biological Process	GO:0007517	muscle organ development	IGI	J:95359
Biological Process	GO:0045445	myoblast differentiation	IDA	J:76817
Biological Process	GO:0045445	myoblast differentiation	IDA	J:82185
Biological Process	GO:0007518	myoblast fate determination	IDA	J:82185
Biological Process	GO:0007520	myoblast fusion	IMP	J:99106
Biological Process	GO:0014904	myotube cell development	ISO	J:164563
Biological Process	GO:0014902	myotube differentiation	IDA	J:214868
Biological Process	GO:0014908	myotube differentiation involved in skeletal muscle regeneration	IMP	J:147
Biological Process	GO:0035562	negative regulation of chromatin binding	IDA	J:228292
Biological Process	GO:0035562	negative regulation of chromatin binding	IMP	J:228292
Biological Process	GO:2000818	negative regulation of myoblast proliferation	IMP	J:99106
Biological Process	GO:0051099	positive regulation of binding	IDA	J:228292
Biological Process	GO:0051099	positive regulation of binding	IMP	J:228292
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:84956
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:94846
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:127524
Biological Process	GO:0051149	positive regulation of muscle cell differentiation	ISO	J:164563
Biological Process	GO:0051149	positive regulation of muscle cell differentiation	IDA	J:243401
Biological Process	GO:0045663	positive regulation of myoblast differentiation	IBA	J:265628
Biological Process	GO:1901741	positive regulation of myoblast fusion	ISO	J:164563
Biological Process	GO:0048743	positive regulation of skeletal muscle fiber development	IBA	J:265628
Biological Process	GO:0043415	positive regulation of skeletal muscle tissue regeneration	IMP	J:116060
Biological Process	GO:1905382	positive regulation of snRNA transcription by RNA polymerase II	IMP	J:259135
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:200312
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:243401
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:69575
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:228292
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:228292
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:97509
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:206594
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:149882
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:217579
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:128715
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:206594
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:177741
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:82185
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:95029
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:198757
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:142475
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:97509
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:206594
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:97509
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:28293
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IMP	J:46849
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IDA	J:46849
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IDA	J:199690
Biological Process	GO:0043484	regulation of RNA splicing	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:154112
Biological Process	GO:0035914	skeletal muscle cell differentiation	NAS	J:173154
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:228292
Biological Process	GO:0035914	skeletal muscle cell differentiation	IDA	J:228292
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:178918
Biological Process	GO:0043503	skeletal muscle fiber adaptation	IMP	J:147457
Biological Process	GO:0048741	skeletal muscle fiber development	IMP	J:147457
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:150130
Biological Process	GO:0007519	skeletal muscle tissue development	IGI	J:16387
Biological Process	GO:0007519	skeletal muscle tissue development	TAS	J:27708
Biological Process	GO:0007519	skeletal muscle tissue development	IDA	J:87788
Biological Process	GO:0007519	skeletal muscle tissue development	IDA	J:76817
Biological Process	GO:0007519	skeletal muscle tissue development	IGI	J:100052
Biological Process	GO:0043403	skeletal muscle tissue regeneration	ISO	J:155856
Biological Process	GO:0043403	skeletal muscle tissue regeneration	IDA	J:228292
Biological Process	GO:0043403	skeletal muscle tissue regeneration	IMP	J:228292
Biological Process	GO:0043403	skeletal muscle tissue regeneration	IMP	J:116060
Biological Process	GO:0051146	striated muscle cell differentiation	IMP	J:116060
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:206594
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:206594
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:206594