GO Annotations Graph

• Symbol: Mme
• Name: membrane metallo endopeptidase
• ID: MGI:97004

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1901612	cardiolipin binding	ISO	J:164563
Molecular Function	GO:0004175	endopeptidase activity	ISO	J:164563
Molecular Function	GO:0008238	exopeptidase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004222	metalloendopeptidase activity	ISO	J:164563
Molecular Function	GO:0004222	metalloendopeptidase activity	IBA	J:265628
Molecular Function	GO:0008237	metallopeptidase activity	IEA	J:60000
Molecular Function	GO:0008237	metallopeptidase activity	IEA	J:72247
Molecular Function	GO:0070012	oligopeptidase activity	ISO	J:155856
Molecular Function	GO:0008233	peptidase activity	IDA	J:100260
Molecular Function	GO:0042277	peptide binding	ISO	J:155856
Molecular Function	GO:0001786	phosphatidylserine binding	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:164563
Cellular Component	GO:0030424	axon	IDA	J:101575
Cellular Component	GO:0005903	brush border	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0030425	dendrite	IDA	J:101575
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:100260
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0044306	neuron projection terminus	IDA	J:101575
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098793	presynapse	ISO	J:164563
Cellular Component	GO:0045202	synapse	IDA	J:101575
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:101575
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Biological Process	GO:0097242	amyloid-beta clearance	ISO	J:155856
Biological Process	GO:0097242	amyloid-beta clearance	IGI	J:114580
Biological Process	GO:0097242	amyloid-beta clearance	ISO	J:164563
Biological Process	GO:0097242	amyloid-beta clearance	IBA	J:265628
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	ISO	J:155856
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	ISO	J:164563
Biological Process	GO:0050435	amyloid-beta metabolic process	IDA	J:101575
Biological Process	GO:0010815	bradykinin catabolic process	ISO	J:164563
Biological Process	GO:0071345	cellular response to cytokine stimulus	ISO	J:164563
Biological Process	GO:0071492	cellular response to UV-A	ISO	J:164563
Biological Process	GO:0071493	cellular response to UV-B	ISO	J:164563
Biological Process	GO:0046449	creatinine metabolic process	ISO	J:164563
Biological Process	GO:0042447	hormone catabolic process	ISO	J:164563
Biological Process	GO:0007611	learning or memory	ISO	J:164563
Biological Process	GO:0061837	neuropeptide processing	ISO	J:164563
Biological Process	GO:0006518	peptide metabolic process	ISO	J:155856
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	IGI	J:114580
Biological Process	GO:0050769	positive regulation of neurogenesis	ISO	J:164563
Biological Process	GO:0030163	protein catabolic process	ISO	J:155856
Biological Process	GO:0016485	protein processing	IBA	J:265628
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0043627	response to estrogen	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	IMP	J:182423
Biological Process	GO:0010814	substance P catabolic process	ISO	J:164563