GO Annotations Graph

• Symbol: Hoxa2
• Name: homeobox A2
• ID: MGI:96174

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:95309
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:95309
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:95309
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619429
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9010499
Cellular Component	GO:0005634	nucleus	IDA	J:57955
Cellular Component	GO:0005634	nucleus	IDA	J:74097
Cellular Component	GO:0005634	nucleus	IDA	J:74097
Cellular Component	GO:0005634	nucleus	IDA	J:74097
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:43763
Biological Process	GO:0035284	brain segmentation	IMP	J:43763
Biological Process	GO:0045165	cell fate commitment	IMP	J:16389
Biological Process	GO:0045165	cell fate commitment	IMP	J:16388
Biological Process	GO:0001709	cell fate determination	IMP	J:102845
Biological Process	GO:0071300	cellular response to retinoic acid	IDA	J:199178
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:54652
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:54652
Biological Process	GO:0009953	dorsal/ventral pattern formation	IGI	J:54652
Biological Process	GO:0048706	embryonic skeletal system development	IDA	J:222399
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IGI	J:95309
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	IMP	J:102845
Biological Process	GO:0042474	middle ear morphogenesis	IMP	J:102845
Biological Process	GO:0042474	middle ear morphogenesis	IMP	J:100238
Biological Process	GO:0042474	middle ear morphogenesis	IGI	J:95309
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:43763
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:43763
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:43763
Biological Process	GO:0008045	motor neuron axon guidance	IMP	J:43763
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0061061	muscle structure development	IDA	J:222399
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:131060
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:131060
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:131060
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:131060
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	IDA	J:171138
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:95309
Biological Process	GO:0030182	neuron differentiation	IMP	J:131060
Biological Process	GO:0002076	osteoblast development	IGI	J:115876
Biological Process	GO:0007389	pattern specification process	IMP	J:16389
Biological Process	GO:0007389	pattern specification process	IMP	J:16388
Biological Process	GO:0060037	pharyngeal system development	IDA	J:222399
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:141247
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0021568	rhombomere 2 development	IMP	J:54625
Biological Process	GO:0021569	rhombomere 3 development	IGI	J:54625
Biological Process	GO:0021658	rhombomere 3 morphogenesis	IMP	J:54652
Biological Process	GO:0007379	segment specification	IMP	J:43763