GO Annotations Graph

• Symbol: Gnai3
• Name: G protein subunit alpha i3
• ID: MGI:95773

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	IBA	J:265628
Molecular Function	GO:0031821	G protein-coupled serotonin receptor binding	ISO	J:155856
Molecular Function	GO:0031683	G-protein beta/gamma-subunit complex binding	IBA	J:265628
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0032794	GTPase activating protein binding	ISO	J:155856
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0003924	GTPase activity	TAS	J:10067
Molecular Function	GO:0019001	guanyl nucleotide binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:218052
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:17193
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:17193
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0005834	heterotrimeric G-protein complex	IBA	J:265628
Cellular Component	GO:0005834	heterotrimeric G-protein complex	TAS	J:10067
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8964229
Cellular Component	GO:0042588	zymogen granule	ISO	J:155856
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	ISO	J:164563
Biological Process	GO:0007212	dopamine receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	TAS	J:10067
Biological Process	GO:0046039	GTP metabolic process	ISO	J:164563
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	ISO	J:155856
Biological Process	GO:0016239	positive regulation of macroautophagy	ISO	J:164563
Biological Process	GO:0033864	positive regulation of NAD(P)H oxidase activity	ISO	J:155856
Biological Process	GO:0032930	positive regulation of superoxide anion generation	ISO	J:155856
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0006906	vesicle fusion	ISO	J:155856