Gabrb2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
MGI:95620

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005254	chloride channel activity	ISO	J:155856
Molecular Function	GO:0005230	extracellular ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0016917	GABA receptor activity	ISO	J:155856
Molecular Function	GO:0016917	GABA receptor activity	ISO	J:164563
Molecular Function	GO:0004890	GABA-A receptor activity	ISO	J:155856
Molecular Function	GO:0004890	GABA-A receptor activity	IBA	J:265628
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	ISO	J:164563
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	IDA	J:281261
Molecular Function	GO:0005237	inhibitory extracellular ligand-gated monoatomic ion channel activity	ISO	J:155856
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0030594	neurotransmitter receptor activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:81920
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:224457
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IMP	J:224457
Cellular Component	GO:0034707	chloride channel complex	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:1902710	GABA receptor complex	ISO	J:155856
Cellular Component	GO:1902711	GABA-A receptor complex	ISO	J:164563
Cellular Component	GO:1902711	GABA-A receptor complex	ISO	J:155856
Cellular Component	GO:1902711	GABA-A receptor complex	IBA	J:265628
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	IC	J:224457
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:226251
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:226251
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:224457
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:224457
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IEA	J:60000
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:226251
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:226251
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0071420	cellular response to histamine	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:224457
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	IMP	J:224457
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:164563
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:155856
Biological Process	GO:0006821	chloride transport	IEA	J:60000
Biological Process	GO:0090102	cochlea development	IMP	J:112951
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	ISO	J:164563
Biological Process	GO:1904862	inhibitory synapse assembly	ISO	J:164563
Biological Process	GO:1904862	inhibitory synapse assembly	IDA	J:281261
Biological Process	GO:0060119	inner ear receptor cell development	IMP	J:112951
Biological Process	GO:0060384	innervation	IMP	J:112951
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IMP	J:224457
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:112951
Biological Process	GO:1901215	negative regulation of neuron death	IMP	J:112951
Biological Process	GO:0050877	nervous system process	IBA	J:265628
Biological Process	GO:0048666	neuron development	IMP	J:112951
Biological Process	GO:0042391	regulation of membrane potential	IBA	J:265628
Biological Process	GO:0043523	regulation of neuron apoptotic process	IMP	J:112951
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	IMP	J:224457
Biological Process	GO:0007605	sensory perception of sound	IMP	J:112951
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0051932	synaptic transmission, GABAergic	NAS	J:320132
Biological Process	GO:0051932	synaptic transmission, GABAergic	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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