Ercc1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
MGI:95412

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:181994
Molecular Function	GO:0005515	protein binding	IPI	J:181994
Molecular Function	GO:0005515	protein binding	IPI	J:181994
Molecular Function	GO:0005515	protein binding	IPI	J:218236
Molecular Function	GO:0005515	protein binding	IPI	J:181994
Molecular Function	GO:0005515	protein binding	IPI	J:181994
Molecular Function	GO:0005515	protein binding	IPI	J:181994
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0000014	single-stranded DNA endodeoxyribonuclease activity	ISO	J:164563
Molecular Function	GO:0001094	TFIID-class transcription factor complex binding	IDA	J:181994
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0070522	ERCC4-ERCC1 complex	ISO	J:164563
Cellular Component	GO:0070522	ERCC4-ERCC1 complex	ISO	J:164563
Cellular Component	GO:0070522	ERCC4-ERCC1 complex	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0000109	nucleotide-excision repair complex	ISO	J:164563
Cellular Component	GO:0000109	nucleotide-excision repair complex	ISO	J:9239
Cellular Component	GO:0000110	nucleotide-excision repair factor 1 complex	ISO	J:164563
Cellular Component	GO:0000110	nucleotide-excision repair factor 1 complex	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IPI	J:181994
Cellular Component	GO:0005634	nucleus	IPI	J:181994
Cellular Component	GO:0005634	nucleus	IPI	J:181994
Cellular Component	GO:0005634	nucleus	IPI	J:181994
Cellular Component	GO:0005634	nucleus	IPI	J:181994
Biological Process	GO:0048468	cell development	IMP	J:62553
Biological Process	GO:0048468	cell development	IMP	J:62553
Biological Process	GO:0008283	cell population proliferation	IMP	J:96496
Biological Process	GO:0051276	chromosome organization	IMP	J:91596
Biological Process	GO:0008340	determination of adult lifespan	IMP	J:117488
Biological Process	GO:0006974	DNA damage response	IMP	J:96496
Biological Process	GO:0006974	DNA damage response	IMP	J:105008
Biological Process	GO:0006974	DNA damage response	IMP	J:72856
Biological Process	GO:0006974	DNA damage response	IMP	J:41161
Biological Process	GO:0006310	DNA recombination	IMP	J:72856
Biological Process	GO:0006310	DNA recombination	ISO	J:73065
Biological Process	GO:0006281	DNA repair	ISO	J:218236
Biological Process	GO:0006281	DNA repair	IMP	J:80586
Biological Process	GO:0006302	double-strand break repair	IMP	J:130019
Biological Process	GO:0006302	double-strand break repair	IMP	J:91596
Biological Process	GO:0006302	double-strand break repair	IMP	J:130019
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:0007281	germ cell development	IMP	J:130019
Biological Process	GO:0007281	germ cell development	IMP	J:130019
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	IMP	J:117488
Biological Process	GO:0036297	interstrand cross-link repair	IMP	J:200022
Biological Process	GO:0045190	isotype switching	IMP	J:92471
Biological Process	GO:0008584	male gonad development	IMP	J:130019
Biological Process	GO:0008584	male gonad development	IMP	J:130019
Biological Process	GO:0006312	mitotic recombination	ISO	J:164563
Biological Process	GO:0006312	mitotic recombination	IBA	J:265628
Biological Process	GO:0035264	multicellular organism growth	IGI	J:181994
Biological Process	GO:0035264	multicellular organism growth	IMP	J:117488
Biological Process	GO:0035264	multicellular organism growth	IGI	J:181994
Biological Process	GO:0035264	multicellular organism growth	IMP	J:181994
Biological Process	GO:1905765	negative regulation of protection from non-homologous end joining at telomere	ISO	J:164563
Biological Process	GO:0032205	negative regulation of telomere maintenance	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:73065
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:9239
Biological Process	GO:0006289	nucleotide-excision repair	IMP	J:15422
Biological Process	GO:0048477	oogenesis	IMP	J:80586
Biological Process	GO:1904431	positive regulation of t-circle formation	IMP	J:222674
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	IMP	J:181994
Biological Process	GO:0035166	post-embryonic hemopoiesis	IMP	J:96496
Biological Process	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	IMP	J:56965
Biological Process	GO:0090399	replicative senescence	IMP	J:41161
Biological Process	GO:0090399	replicative senescence	IMP	J:118249
Biological Process	GO:0006979	response to oxidative stress	ISO	J:164563
Biological Process	GO:0010165	response to X-ray	IMP	J:105008
Biological Process	GO:0007283	spermatogenesis	IMP	J:80586
Biological Process	GO:0006949	syncytium formation	IMP	J:62553
Biological Process	GO:0090656	t-circle formation	IMP	J:222674
Biological Process	GO:0061819	telomeric DNA-containing double minutes formation	ISO	J:164563
Biological Process	GO:0009650	UV protection	IMP	J:56965
Biological Process	GO:0009650	UV protection	IMP	J:115849
Biological Process	GO:0009650	UV protection	IMP	J:15422
Biological Process	GO:0070914	UV-damage excision repair	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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