GO Annotations Graph

• Symbol: Eif3a
• Name: eukaryotic translation initiation factor 3, subunit A
• ID: MGI:95301

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:147897
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003743	translation initiation factor activity	IDA	J:148056
Molecular Function	GO:0003743	translation initiation factor activity	ISO	J:164563
Molecular Function	GO:0003743	translation initiation factor activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	IDA	J:148056
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	ISO	J:164563
Cellular Component	GO:0071540	eukaryotic translation initiation factor 3 complex, eIF3e	IBA	J:265628
Cellular Component	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	IBA	J:265628
Cellular Component	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	IDA	J:204915
Cellular Component	GO:0005874	microtubule	ISO	J:155856
Cellular Component	GO:0043614	multi-eIF complex	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	EXP	J:263419
Cellular Component	GO:0014069	postsynaptic density	IDA	J:263419
Cellular Component	GO:0014069	postsynaptic density	IDA	J:263419
Cellular Component	GO:0014069	postsynaptic density	EXP	J:263419
Biological Process	GO:0001732	formation of cytoplasmic translation initiation complex	ISO	J:164563
Biological Process	GO:0001732	formation of cytoplasmic translation initiation complex	IDA	J:148056
Biological Process	GO:0001732	formation of cytoplasmic translation initiation complex	IBA	J:265628
Biological Process	GO:0075522	IRES-dependent viral translational initiation	ISO	J:164563
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0006412	translation	IEA	J:60000
Biological Process	GO:0002188	translation reinitiation	IBA	J:265628
Biological Process	GO:0006413	translational initiation	IEA	J:60000
Biological Process	GO:0075525	viral translational termination-reinitiation	ISO	J:164563