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GO Annotations Graph
Symbol
Name
ID
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
MGI:95299

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003676nucleic acid bindingIEAJ:72247
Molecular FunctionGO:0044822poly(A) RNA bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:93997
Molecular FunctionGO:0005515protein bindingIPIJ:200502
Molecular FunctionGO:0043022ribosome bindingISOJ:164563
Molecular FunctionGO:0043022ribosome bindingIBAJ:161428
Molecular FunctionGO:0003723RNA bindingIEAJ:60000
Molecular FunctionGO:0003723RNA bindingIEAJ:72247
Molecular FunctionGO:0003743translation initiation factor activityIBAJ:161428
Molecular FunctionGO:0003743translation initiation factor activityISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:82058
Cellular ComponentGO:0010494cytoplasmic stress granuleIDAJ:162904
Cellular ComponentGO:0033290eukaryotic 48S preinitiation complexIBAJ:161428
Cellular ComponentGO:0005850eukaryotic translation initiation factor 2 complexIBAJ:161428
Cellular ComponentGO:0005850eukaryotic translation initiation factor 2 complexISOJ:155856
Cellular ComponentGO:0005851colocalizes_with
eukaryotic translation initiation factor 2B complex
ISOJ:164563
Cellular ComponentGO:0005851eukaryotic translation initiation factor 2B complexIBAJ:161428
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0097451glial limiting end-footISOJ:155856
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0043614multi-eIF complexIBAJ:161428
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:82058
Cellular ComponentGO:0005840ribosomeIBAJ:161428
Cellular ComponentGO:0044207translation initiation ternary complexISOJ:155856
Biological ProcessGO:0034198cellular response to amino acid starvationIDAJ:99455
Biological ProcessGO:0034605cellular response to heatISOJ:155856
Biological ProcessGO:0034644cellular response to UVIDAJ:227395
Biological ProcessGO:0098779mitophagy in response to mitochondrial depolarizationISOJ:164563
Biological ProcessGO:0032057negative regulation of translational initiation in response to stressIDAJ:227395
Biological ProcessGO:0002230positive regulation of defense response to virus by hostISOJ:164563
Biological ProcessGO:1901216positive regulation of neuron deathISOJ:155856
Biological ProcessGO:2000676positive regulation of type B pancreatic cell apoptotic processISOJ:155856
Biological ProcessGO:0046777protein autophosphorylationIDAJ:146172
Biological ProcessGO:0006417regulation of translationIEAJ:60000
Biological ProcessGO:0043558regulation of translational initiation in response to stressIDAJ:100824
Biological ProcessGO:0034976response to endoplasmic reticulum stressIDAJ:99455
Biological ProcessGO:0006412translationIDAJ:107108
Biological ProcessGO:0006412translationIDAJ:82058
Biological ProcessGO:0006412translationIDAJ:62257
Biological ProcessGO:0006413translational initiationIBAJ:161428
Biological ProcessGO:0098792xenophagyISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory