GO Annotations Graph

• Symbol: Dhh
• Name: desert hedgehog
• ID: MGI:94891

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005113	patched binding	ISO	J:164563
Molecular Function	GO:0005113	patched binding	IPI	J:50930
Molecular Function	GO:0005113	patched binding	ISO	J:164563
Molecular Function	GO:0005113	patched binding	IBA	J:265628
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:53760
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9692139
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0001708	cell fate specification	IBA	J:265628
Biological Process	GO:0007267	cell-cell signaling	IEA	J:72247
Biological Process	GO:0016539	intein-mediated protein splicing	IEA	J:72247
Biological Process	GO:0033327	Leydig cell differentiation	IGI	J:129625
Biological Process	GO:0033327	Leydig cell differentiation	IGI	J:129625
Biological Process	GO:0033327	Leydig cell differentiation	IMP	J:82007
Biological Process	GO:0008584	male gonad development	IMP	J:65900
Biological Process	GO:0008584	male gonad development	IMP	J:57914
Biological Process	GO:0030238	male sex determination	IGI	J:129625
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0001649	osteoblast differentiation	IDA	J:226676
Biological Process	GO:0038001	paracrine signaling	IMP	J:290862
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	ISO	J:164563
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	ISO	J:164563
Biological Process	GO:0016540	protein autoprocessing	IEA	J:72247
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0010468	regulation of gene expression	IBA	J:265628
Biological Process	GO:0050810	regulation of steroid biosynthetic process	IGI	J:129625
Biological Process	GO:0014044	Schwann cell development	IMP	J:57341
Biological Process	GO:0007224	smoothened signaling pathway	IBA	J:265628
Biological Process	GO:0007224	smoothened signaling pathway	IDA	J:226676
Biological Process	GO:0007286	spermatid development	IMP	J:129625
Biological Process	GO:0007283	spermatogenesis	IMP	J:57914