GO Annotations Graph

• Symbol: Xrn1
• Name: 5'-3' exoribonuclease 1
• ID: MGI:891964

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008409	5'-3' exonuclease activity	IEA	J:72247
Molecular Function	GO:0004534	5'-3' RNA exonuclease activity	IDA	J:39219
Molecular Function	GO:0004534	5'-3' RNA exonuclease activity	ISO	J:164563
Molecular Function	GO:0004534	5'-3' RNA exonuclease activity	TAS	J:41259
Molecular Function	GO:0004534	5'-3' RNA exonuclease activity	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0004527	exonuclease activity	IEA	J:72247
Molecular Function	GO:0004527	exonuclease activity	IEA	J:60000
Molecular Function	GO:0051880	G-quadruplex DNA binding	IDA	J:39219
Molecular Function	GO:0002151	G-quadruplex RNA binding	IDA	J:39219
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:243742
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:39219
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0000932	P-body	ISO	J:155856
Cellular Component	GO:0000932	P-body	IDA	J:139263
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0071044	histone mRNA catabolic process	ISO	J:164563
Biological Process	GO:0051321	meiotic cell cycle	NAS	J:41259
Biological Process	GO:0017148	negative regulation of translation	ISO	J:155856
Biological Process	GO:0071028	nuclear mRNA surveillance	ISO	J:164563
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	ISO	J:164563
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	IBA	J:265628
Biological Process	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	IDA	J:39219
Biological Process	GO:0006396	RNA processing	TAS	J:39219
Biological Process	GO:0016075	rRNA catabolic process	ISO	J:164563
Biological Process	GO:0016075	rRNA catabolic process	IBA	J:265628
Biological Process	GO:0000723	telomere maintenance	NAS	J:41259
Biological Process	GO:0000723	telomere maintenance	IC	J:39219