GO Annotations Graph

• Symbol: Cdx2
• Name: caudal type homeobox 2
• ID: MGI:88361

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:179218
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IBA	J:265628
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:104800
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0008327	methyl-CpG binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:104800
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:304703
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:304761
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:154112
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:93217
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:199456
Cellular Component	GO:0005634	nucleus	IDA	J:222297
Cellular Component	GO:0005634	nucleus	IDA	J:185555
Cellular Component	GO:0005634	nucleus	IDA	J:204143
Cellular Component	GO:0005634	nucleus	IDA	J:206154
Cellular Component	GO:0005634	nucleus	IDA	J:194646
Cellular Component	GO:0005634	nucleus	IDA	J:184811
Cellular Component	GO:0005634	nucleus	IDA	J:166464
Cellular Component	GO:0005634	nucleus	IDA	J:193806
Cellular Component	GO:0005634	nucleus	IDA	J:203796
Cellular Component	GO:0005634	nucleus	IDA	J:136803
Cellular Component	GO:0005634	nucleus	IDA	J:104800
Cellular Component	GO:0005634	nucleus	IDA	J:154112
Cellular Component	GO:0005634	nucleus	IDA	J:117056
Cellular Component	GO:0005634	nucleus	IDA	J:136803
Cellular Component	GO:0032991	protein-containing complex	IDA	J:154112
Cellular Component	GO:0017053	transcription repressor complex	IDA	J:104800
Biological Process	GO:0009887	animal organ morphogenesis	IBA	J:265628
Biological Process	GO:0009948	anterior/posterior axis specification	IBA	J:265628
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:154781
Biological Process	GO:0001824	blastocyst development	IMP	J:98502
Biological Process	GO:0001568	blood vessel development	IGI	J:104372
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0009790	embryo development	IBA	J:265628
Biological Process	GO:0008333	endosome to lysosome transport	IMP	J:161201
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IMP	J:161201
Biological Process	GO:0060575	intestinal epithelial cell differentiation	IMP	J:179218
Biological Process	GO:0060711	labyrinthine layer development	IGI	J:154781
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:104800
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:104800
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:104800
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:104800
Biological Process	GO:0007389	pattern specification process	IMP	J:75947
Biological Process	GO:0001890	placenta development	IGI	J:104372
Biological Process	GO:0001890	placenta development	IGI	J:104372
Biological Process	GO:0045597	positive regulation of cell differentiation	IMP	J:179732
Biological Process	GO:0045597	positive regulation of cell differentiation	IDA	J:104800
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:304761
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:304703
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0014807	regulation of somitogenesis	IMP	J:179218
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:154112
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:162675
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:104800
Biological Process	GO:0048863	stem cell differentiation	IMP	J:162675
Biological Process	GO:0001829	trophectodermal cell differentiation	IDA	J:222297
Biological Process	GO:0001829	trophectodermal cell differentiation	IMP	J:162675
Biological Process	GO:0001829	trophectodermal cell differentiation	IDA	J:104800
Biological Process	GO:0001829	trophectodermal cell differentiation	IMP	J:222297
Biological Process	GO:0001829	trophectodermal cell differentiation	IMP	J:98502
Biological Process	GO:0001829	trophectodermal cell differentiation	IMP	J:162675
Biological Process	GO:0001829	trophectodermal cell differentiation	IDA	J:104800