GO Annotations Graph

• Symbol: C1qa
• Name: complement component 1, q subcomponent, alpha polypeptide
• ID: MGI:88223

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:186158
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0005602	complement component C1 complex	NAS	J:319954
Cellular Component	GO:0062167	complement component C1q complex	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	NAS	J:319954
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0098794	postsynapse	IGI	J:269645
Cellular Component	GO:0045202	synapse	IDA	J:269645
Cellular Component	GO:0045202	synapse	IGI	J:137589
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:137589
Biological Process	GO:0007568	aging	IGI	J:102186
Biological Process	GO:0048143	astrocyte activation	IGI	J:102186
Biological Process	GO:0006958	complement activation, classical pathway	NAS	J:320127
Biological Process	GO:0006958	complement activation, classical pathway	ISO	J:164563
Biological Process	GO:0006958	complement activation, classical pathway	IMP	J:75709
Biological Process	GO:0150062	complement-mediated synapse pruning	IMP	J:137589
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0001774	microglial cell activation	IGI	J:102186
Biological Process	GO:0016322	neuron remodeling	IMP	J:137589
Biological Process	GO:1901216	positive regulation of neuron death	IGI	J:102186
Biological Process	GO:0050808	synapse organization	IGI	J:269645
Biological Process	GO:0098883	synapse pruning	IGI	J:269645
Biological Process	GO:0150064	vertebrate eye-specific patterning	IMP	J:137589