GO Annotations Graph

• Symbol: Braf
• Name: Braf transforming gene
• ID: MGI:88190

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0004708	MAP kinase kinase activity	ISO	J:164563
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:161180
Molecular Function	GO:0005515	protein binding	IPI	J:277858
Molecular Function	GO:0005515	protein binding	IPI	J:183162
Molecular Function	GO:0005515	protein binding	IPI	J:247467
Molecular Function	GO:0005515	protein binding	IPI	J:192986
Molecular Function	GO:0005515	protein binding	IPI	J:101397
Molecular Function	GO:0005515	protein binding	IPI	J:101397
Molecular Function	GO:0005515	protein binding	IPI	J:101397
Molecular Function	GO:0004672	protein kinase activity	IDA	J:186066
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0044297	cell body	IDA	J:112971
Cellular Component	GO:0005737	cytoplasm	IDA	J:98531
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	IDA	J:101397
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:112971
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:98531
Biological Process	GO:0046632	alpha-beta T cell differentiation	IMP	J:194392
Biological Process	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	IMP	J:131579
Biological Process	GO:0043367	CD4-positive, alpha-beta T cell differentiation	IMP	J:194392
Biological Process	GO:0030154	cell differentiation	IGI	J:61360
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:164563
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	IDA	J:192986
Biological Process	GO:0072577	endothelial cell apoptotic process	IMP	J:41257
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:117308
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:196950
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:107042
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:194392
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:91604
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:194392
Biological Process	GO:0090150	establishment of protein localization to membrane	ISO	J:164563
Biological Process	GO:0060324	face development	IGI	J:144862
Biological Process	GO:0060323	head morphogenesis	IMP	J:213126
Biological Process	GO:0060291	long-term synaptic potentiation	IMP	J:107042
Biological Process	GO:0000165	MAPK cascade	ISO	J:164563
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0002318	myeloid progenitor cell differentiation	IMP	J:117308
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	IMP	J:41257
Biological Process	GO:0010764	negative regulation of fibroblast migration	IMP	J:91604
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:112971
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:112971
Biological Process	GO:2000301	negative regulation of synaptic vesicle exocytosis	IMP	J:196950
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0048680	positive regulation of axon regeneration	IDA	J:213126
Biological Process	GO:0050772	positive regulation of axonogenesis	IGI	J:213126
Biological Process	GO:0050772	positive regulation of axonogenesis	IMP	J:213126
Biological Process	GO:0050772	positive regulation of axonogenesis	IGI	J:213126
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:131579
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:117308
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:91604
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:196950
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:107042
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:194392
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IDA	J:187371
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:213126
Biological Process	GO:0010828	positive regulation of glucose transmembrane transport	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0051496	positive regulation of stress fiber assembly	IMP	J:91604
Biological Process	GO:0051496	positive regulation of stress fiber assembly	IGI	J:91604
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	IMP	J:91604
Biological Process	GO:0043368	positive T cell selection	IMP	J:194392
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:186066
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0048679	regulation of axon regeneration	IGI	J:213126
Biological Process	GO:0048679	regulation of axon regeneration	IGI	J:213126
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:188570
Biological Process	GO:0045580	regulation of T cell differentiation	IMP	J:131579
Biological Process	GO:0051591	response to cAMP	ISO	J:155856
Biological Process	GO:0043434	response to peptide hormone	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0035019	somatic stem cell population maintenance	IGI	J:196225
Biological Process	GO:0043149	stress fiber assembly	IMP	J:91604
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	IMP	J:91604
Biological Process	GO:0016079	synaptic vesicle exocytosis	IMP	J:196950
Biological Process	GO:0033077	T cell differentiation in thymus	IMP	J:194392
Biological Process	GO:0050852	T cell receptor signaling pathway	IDA	J:131579
Biological Process	GO:0048538	thymus development	IGI	J:144862
Biological Process	GO:0030878	thyroid gland development	IGI	J:144862
Biological Process	GO:0070413	trehalose metabolism in response to stress	ISO	J:164563
Biological Process	GO:0008542	visual learning	IMP	J:107042