GO Annotations Graph

• Symbol: Avpr2
• Name: arginine vasopressin receptor 2
• ID: MGI:88123

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0042277	peptide binding	IBA	J:265628
Molecular Function	GO:0005000	vasopressin receptor activity	ISO	J:164563
Molecular Function	GO:0005000	vasopressin receptor activity	IBA	J:265628
Cellular Component	GO:0030139	endocytic vesicle	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0032870	cellular response to hormone stimulus	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IMP	J:56156
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0035814	negative regulation of renal sodium excretion	ISO	J:155856
Biological Process	GO:0035811	negative regulation of urine volume	ISO	J:155856
Biological Process	GO:0045777	positive regulation of blood pressure	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0003084	positive regulation of systemic arterial blood pressure	ISO	J:155856
Biological Process	GO:0045907	positive regulation of vasoconstriction	IBA	J:265628
Biological Process	GO:0001992	regulation of systemic arterial blood pressure by vasopressin	IBA	J:265628
Biological Process	GO:0034097	response to cytokine	IMP	J:56156
Biological Process	GO:0034097	response to cytokine	IMP	J:56156
Biological Process	GO:0034097	response to cytokine	IMP	J:56156
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0032609	type II interferon production	IMP	J:56156