Actb GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Actb
actin, beta
MGI:87904

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0019894	kinesin binding	ISO	J:164563
Molecular Function	GO:0050998	nitric-oxide synthase binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:105078
Molecular Function	GO:0005515	protein binding	IPI	J:122748
Molecular Function	GO:0005515	protein binding	IPI	J:222132
Molecular Function	GO:0005515	protein binding	IPI	J:144029
Molecular Function	GO:0005515	protein binding	IPI	J:233627
Molecular Function	GO:0005515	protein binding	IPI	J:261913
Molecular Function	GO:0005515	protein binding	IPI	J:177167
Molecular Function	GO:0005515	protein binding	IPI	J:165948
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0098973	structural constituent of postsynaptic actin cytoskeleton	ISO	J:164563
Molecular Function	GO:0030957	Tat protein binding	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0043296	apical junction complex	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0140092	bBAF complex	NAS	J:156242
Cellular Component	GO:0035060	brahma complex	NAS	J:35263
Cellular Component	GO:0005903	brush border	IDA	J:300338
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0044305	calyx of Held	IMP	J:263458
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0000785	chromatin	NAS	J:283189
Cellular Component	GO:0000785	chromatin	NAS	J:320042
Cellular Component	GO:0030863	cortical cytoskeleton	IDA	J:138919
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:252003
Cellular Component	GO:0005737	cytoplasm	IDA	J:255730
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IDA	J:252003
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2316348
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2316351
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0005829	cytosol	IDA	J:75807
Cellular Component	GO:0005829	cytosol	IDA	J:93333
Cellular Component	GO:0140288	GBAF complex	NAS	J:283189
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	NAS	J:320056
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0071565	nBAF complex	NAS	J:132101
Cellular Component	GO:0071564	npBAF complex	NAS	J:35263
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	NAS	J:320261
Cellular Component	GO:0000786	nucleosome	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:255730
Cellular Component	GO:0002102	podosome	ISO	J:155856
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:0016586	RSC-type complex	NAS	J:35263
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0001725	stress fiber	ISO	J:155856
Cellular Component	GO:0016514	SWI/SNF complex	NAS	J:35263
Cellular Component	GO:0070160	tight junction	ISO	J:164563
Biological Process	GO:0034333	adherens junction assembly	ISO	J:164563
Biological Process	GO:0045176	apical protein localization	ISO	J:164563
Biological Process	GO:0007409	axonogenesis	ISO	J:155856
Biological Process	GO:0048870	cell motility	ISO	J:164563
Biological Process	GO:0072749	cellular response to cytochalasin B	ISO	J:164563
Biological Process	GO:0071257	cellular response to electrical stimulus	ISO	J:155856
Biological Process	GO:0006338	chromatin remodeling	NAS	J:283189
Biological Process	GO:0006338	chromatin remodeling	NAS	J:320039
Biological Process	GO:0007163	establishment or maintenance of cell polarity	ISO	J:164563
Biological Process	GO:0016573	histone acetylation	NAS	J:320265
Biological Process	GO:0043968	histone H2A acetylation	ISO	J:164563
Biological Process	GO:0043967	histone H4 acetylation	ISO	J:164563
Biological Process	GO:0001738	morphogenesis of a polarized epithelium	ISO	J:164563
Biological Process	GO:0045596	negative regulation of cell differentiation	NAS	J:268334
Biological Process	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	IC	J:144029
Biological Process	GO:0032091	negative regulation of protein binding	IDA	J:144029
Biological Process	GO:0045597	positive regulation of cell differentiation	NAS	J:156242
Biological Process	GO:0045597	positive regulation of cell differentiation	NAS	J:74389
Biological Process	GO:0008284	positive regulation of cell population proliferation	NAS	J:283189
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:319957
Biological Process	GO:2000781	positive regulation of double-strand break repair	NAS	J:319964
Biological Process	GO:2000781	positive regulation of double-strand break repair	NAS	J:319983
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0045663	positive regulation of myoblast differentiation	NAS	J:319991
Biological Process	GO:0045663	positive regulation of myoblast differentiation	NAS	J:320040
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:268334
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:147141
Biological Process	GO:0045582	positive regulation of T cell differentiation	NAS	J:131676
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0071896	protein localization to adherens junction	ISO	J:164563
Biological Process	GO:0042981	regulation of apoptotic process	NAS	J:320265
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:155856
Biological Process	GO:2000779	regulation of double-strand break repair	NAS	J:320265
Biological Process	GO:0070316	regulation of G0 to G1 transition	NAS	J:74389
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	NAS	J:320113
Biological Process	GO:0030071	regulation of mitotic metaphase/anaphase transition	NAS	J:319964
Biological Process	GO:0030071	regulation of mitotic metaphase/anaphase transition	NAS	J:198738
Biological Process	GO:0051621	regulation of norepinephrine uptake	ISO	J:164563
Biological Process	GO:0051621	regulation of norepinephrine uptake	ISO	J:155856
Biological Process	GO:2000819	regulation of nucleotide-excision repair	NAS	J:320041
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:320308
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:132101
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:68501
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:320112
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:283189
Biological Process	GO:0150111	regulation of transepithelial transport	ISO	J:164563
Biological Process	GO:0022898	regulation of transmembrane transporter activity	ISO	J:164563
Biological Process	GO:0022898	regulation of transmembrane transporter activity	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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