GO Annotations Graph

• Symbol: Sorbs1
• Name: sorbin and SH3 domain containing 1
• ID: MGI:700014

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005158	insulin receptor binding	IPI	J:46223
Molecular Function	GO:0005158	insulin receptor binding	IDA	J:46223
Molecular Function	GO:0005158	insulin receptor binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:114794
Molecular Function	GO:0005515	protein binding	IPI	J:116379
Molecular Function	GO:0005515	protein binding	IPI	J:77887
Molecular Function	GO:0005515	protein binding	IPI	J:45798
Molecular Function	GO:0005515	protein binding	IPI	J:46223
Molecular Function	GO:0005515	protein binding	IPI	J:200425
Molecular Function	GO:0005515	protein binding	IPI	J:189995
Molecular Function	GO:0005515	protein binding	IPI	J:235913
Molecular Function	GO:0019901	protein kinase binding	IDA	J:45798
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	ISO	J:164563
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	IPI	J:46223
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:46223
Cellular Component	GO:0005912	adherens junction	IDA	J:116379
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0030055	cell-substrate junction	IDA	J:116379
Cellular Component	GO:0030055	cell-substrate junction	IBA	J:265628
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IDA	J:189995
Cellular Component	GO:0005829	cytosol	IDA	J:46223
Cellular Component	GO:0016600	flotillin complex	IDA	J:114794
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:46223
Cellular Component	GO:0045121	membrane raft	IDA	J:114794
Cellular Component	GO:0016363	nuclear matrix	IDA	J:189995
Cellular Component	GO:0005634	nucleus	IDA	J:189995
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	IDA	J:45798
Cellular Component	GO:0045202	synapse	IDA	J:235913
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	IGI	J:235913
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	IGI	J:235913
Biological Process	GO:0031589	cell-substrate adhesion	IBA	J:265628
Biological Process	GO:0032869	cellular response to insulin stimulus	IMP	J:114794
Biological Process	GO:0048041	focal adhesion assembly	IDA	J:45798
Biological Process	GO:0008286	insulin receptor signaling pathway	IDA	J:46223
Biological Process	GO:0046326	positive regulation of glucose import	IMP	J:114794
Biological Process	GO:0046326	positive regulation of glucose import	IDA	J:114794
Biological Process	GO:0045725	positive regulation of glycogen biosynthetic process	IMP	J:114794
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	IDA	J:114794
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	IMP	J:114794
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	IMP	J:114794
Biological Process	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering	IGI	J:235913
Biological Process	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering	IGI	J:235913
Biological Process	GO:0043149	stress fiber assembly	IDA	J:45798