GO Annotations Graph

• Symbol: Catsper4
• Name: cation channel, sperm associated 4
• ID: MGI:3043288

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005227	calcium activated cation channel activity	IEA	J:72247
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:116406
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:116406
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0001669	acrosomal vesicle	IBA	J:265628
Cellular Component	GO:0001669	acrosomal vesicle	IDA	J:117731
Cellular Component	GO:0001669	acrosomal vesicle	IDA	J:117731
Cellular Component	GO:0036128	CatSper complex	IDA	J:314092
Cellular Component	GO:0036128	CatSper complex	IDA	J:182472
Cellular Component	GO:0036128	CatSper complex	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0031514	motile cilium	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0097228	sperm principal piece	IDA	J:314092
Cellular Component	GO:0097228	sperm principal piece	IBA	J:265628
Cellular Component	GO:0097228	sperm principal piece	IDA	J:116406
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:116406
Biological Process	GO:0030317	flagellated sperm motility	IBA	J:265628
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:116406
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006814	sodium ion transport	IBA	J:265628
Biological Process	GO:0006814	sodium ion transport	IMP	J:116406
Biological Process	GO:0048240	sperm capacitation	IBA	J:265628
Biological Process	GO:0048240	sperm capacitation	IMP	J:116406
Biological Process	GO:0007283	spermatogenesis	IEA	J:60000
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247