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GO Annotations Graph
Symbol
Name
ID
Hdac4
histone deacetylase 4
MGI:3036234

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0033613activating transcription factor bindingISOJ:164563
Molecular FunctionGO:0003682chromatin bindingIDAJ:215277
Molecular FunctionGO:0001047core promoter bindingISOJ:164563
Molecular FunctionGO:0001047core promoter bindingISOJ:155856
Molecular FunctionGO:0003677DNA bindingIDAJ:102395
Molecular FunctionGO:0004407histone deacetylase activityISOJ:155856
Molecular FunctionGO:0004407histone deacetylase activityISOJ:73065
Molecular FunctionGO:0042826histone deacetylase bindingISOJ:164563
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0032041NAD-dependent histone deacetylase activity (H3-K14 specific)IEAJ:72245
Molecular FunctionGO:0030955potassium ion bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:87326
Molecular FunctionGO:0005515protein bindingIPIJ:136003
Molecular FunctionGO:0005515protein bindingIPIJ:123041
Molecular FunctionGO:0005515protein bindingIPIJ:138150
Molecular FunctionGO:0005515protein bindingIPIJ:131022
Molecular FunctionGO:0005515protein bindingIPIJ:138150
Molecular FunctionGO:0005515protein bindingIPIJ:102395
Molecular FunctionGO:0005515protein bindingIPIJ:99840
Molecular FunctionGO:0005515protein bindingIPIJ:94631
Molecular FunctionGO:0005515protein bindingIPIJ:94631
Molecular FunctionGO:0005515protein bindingIPIJ:95385
Molecular FunctionGO:0005515protein bindingIPIJ:182752
Molecular FunctionGO:0033558protein deacetylase activityIDAJ:135324
Molecular FunctionGO:0033558protein deacetylase activityISOJ:164563
Molecular FunctionGO:0019901protein kinase bindingIPIJ:121892
Molecular FunctionGO:0070491repressing transcription factor bindingISOJ:164563
Molecular FunctionGO:0001025RNA polymerase III transcription factor bindingISOJ:164563
Molecular FunctionGO:0043565contributes_to
sequence-specific DNA binding
ISOJ:164563
Molecular FunctionGO:0003714transcription corepressor activityIGIJ:99840
Molecular FunctionGO:0008134transcription factor bindingISOJ:164563
Molecular FunctionGO:0008134transcription factor bindingISOJ:155856
Molecular FunctionGO:0008134transcription factor bindingIPIJ:172910
Molecular FunctionGO:0044212contributes_to
transcription regulatory region DNA binding
ISOJ:164563
Molecular FunctionGO:0008270zinc ion bindingISOJ:164563
Cellular ComponentGO:0031672A bandISOJ:73065
Cellular ComponentGO:0042641actomyosinIDAJ:135324
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:182752
Cellular ComponentGO:0005737cytoplasmIMPJ:153383
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005829cytosolIDAJ:135003
Cellular ComponentGO:0000118histone deacetylase complexISOJ:164563
Cellular ComponentGO:0031594neuromuscular junctionIDAJ:128352
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:182752
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005634nucleusIMPJ:153383
Cellular ComponentGO:0043234protein complexISOJ:155856
Cellular ComponentGO:0030017sarcomereISOJ:155856
Cellular ComponentGO:0030017sarcomereISOJ:73065
Cellular ComponentGO:0017053transcriptional repressor complexISOJ:164563
Cellular ComponentGO:0030018Z discISOJ:73065
Biological ProcessGO:0016568chromatin modificationIEAJ:60000
Biological ProcessGO:0016568chromatin modificationIEAJ:72247
Biological ProcessGO:0006338chromatin remodelingISOJ:164563
Biological ProcessGO:0016575histone deacetylationISOJ:164563
Biological ProcessGO:0016575histone deacetylationISOJ:155856
Biological ProcessGO:0070932histone H3 deacetylationISOJ:164563
Biological ProcessGO:0070933histone H4 deacetylationISOJ:164563
Biological ProcessGO:0008285negative regulation of cell proliferationIDAJ:94631
Biological ProcessGO:0008285negative regulation of cell proliferationIMPJ:94631
Biological ProcessGO:0045820negative regulation of glycolytic processIMPJ:153383
Biological ProcessGO:0010832negative regulation of myotube differentiationISOJ:164563
Biological ProcessGO:0045668negative regulation of osteoblast differentiationIMPJ:99840
Biological ProcessGO:0043433negative regulation of sequence-specific DNA binding transcription factor activityISOJ:164563
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:73065
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIGIJ:119152
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIGIJ:94631
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIGIJ:99840
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIGIJ:95385
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIDAJ:128352
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:73065
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedIDAJ:102395
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedIMPJ:87326
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0002076osteoblast developmentIMPJ:99840
Biological ProcessGO:0034983peptidyl-lysine deacetylationISOJ:164563
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:164563
Biological ProcessGO:0010592positive regulation of lamellipodium assemblyISOJ:155856
Biological ProcessGO:0043525positive regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:0033235positive regulation of protein sumoylationISOJ:164563
Biological ProcessGO:1903428positive regulation of reactive oxygen species biosynthetic processISOJ:155856
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISOJ:164563
Biological ProcessGO:0014911positive regulation of smooth muscle cell migrationISOJ:155856
Biological ProcessGO:0048661positive regulation of smooth muscle cell proliferationISOJ:155856
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIMPJ:153383
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIMPJ:153383
Biological ProcessGO:0010882regulation of cardiac muscle contraction by calcium ion signalingIMPJ:135324
Biological ProcessGO:0040029regulation of gene expression, epigeneticISOJ:164563
Biological ProcessGO:0043393regulation of protein bindingISOJ:164563
Biological ProcessGO:0048742regulation of skeletal muscle fiber developmentIGIJ:127416
Biological ProcessGO:0051153regulation of striated muscle cell differentiationIGIJ:127416
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0014894response to denervation involved in regulation of muscle adaptationIMPJ:153383
Biological ProcessGO:0042493response to drugISOJ:155856
Biological ProcessGO:0070555response to interleukin-1ISOJ:164563
Biological ProcessGO:0001501skeletal system developmentIMPJ:94631
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory