GO Annotations Graph

• Symbol: Plk5
• Name: polo like kinase 5
• ID: MGI:3026984

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Cellular Component	GO:0005813	centrosome	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	IDA	J:173149
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0000922	spindle pole	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0071363	cellular response to growth factor stimulus	ISO	J:164563
Biological Process	GO:0002357	defense response to tumor cell	ISO	J:164563
Biological Process	GO:0002357	defense response to tumor cell	IDA	J:170612
Biological Process	GO:0006974	DNA damage response	IDA	J:173149
Biological Process	GO:0006974	DNA damage response	IBA	J:265628
Biological Process	GO:0007052	mitotic spindle organization	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:173149
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:170612
Biological Process	GO:0010976	positive regulation of neuron projection development	IDA	J:170612
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0042981	regulation of apoptotic process	IMP	J:170612
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:164563
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	IMP	J:173149
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	IMP	J:170612
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	IBA	J:265628