Mavs GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Mavs
mitochondrial antiviral signaling protein
MGI:2444773

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050700	CARD domain binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0140693	molecular condensate scaffold activity	ISO	J:164563
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:200433
Molecular Function	GO:0005515	protein binding	IPI	J:257328
Molecular Function	GO:0005515	protein binding	IPI	J:144594
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0039552	RIG-I binding	ISO	J:164563
Molecular Function	GO:0035591	signaling adaptor activity	ISO	J:164563
Molecular Function	GO:0035591	signaling adaptor activity	IMP	J:167950
Molecular Function	GO:0035591	signaling adaptor activity	IDA	J:197368
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	TAS	Reactome:R-MMU-936387
Cellular Component	GO:0005739	mitochondrion	IDA	J:167950
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:197368
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	IDA	J:280922
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	IDA	J:167950
Cellular Component	GO:0005777	peroxisome	IDA	J:186390
Biological Process	GO:0002218	activation of innate immune response	ISO	J:164563
Biological Process	GO:0140374	antiviral innate immune response	ISO	J:164563
Biological Process	GO:0071360	cellular response to exogenous dsRNA	ISO	J:164563
Biological Process	GO:0035458	cellular response to interferon-beta	ISO	J:280922
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	ISO	J:164563
Biological Process	GO:0042742	defense response to bacterium	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	IMP	J:167950
Biological Process	GO:0045071	negative regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production	ISO	J:164563
Biological Process	GO:0002230	positive regulation of defense response to virus by host	ISO	J:164563
Biological Process	GO:0002230	positive regulation of defense response to virus by host	IMP	J:139074
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0032727	positive regulation of interferon-alpha production	ISO	J:164563
Biological Process	GO:0032727	positive regulation of interferon-alpha production	IMP	J:280922
Biological Process	GO:0032728	positive regulation of interferon-beta production	ISO	J:164563
Biological Process	GO:0032728	positive regulation of interferon-beta production	IMP	J:280922
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IMP	J:280922
Biological Process	GO:0032757	positive regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0071660	positive regulation of IP-10 production	ISO	J:164563
Biological Process	GO:0002735	positive regulation of myeloid dendritic cell cytokine production	IMP	J:173994
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	ISO	J:164563
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	IDA	J:197368
Biological Process	GO:0090073	positive regulation of protein homodimerization activity	ISO	J:280922
Biological Process	GO:0042307	positive regulation of protein import into nucleus	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0060760	positive regulation of response to cytokine stimulus	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032481	positive regulation of type I interferon production	ISO	J:164563
Biological Process	GO:0032481	positive regulation of type I interferon production	IMP	J:139074
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0070585	protein localization to mitochondrion	IDA	J:197368
Biological Process	GO:0070585	protein localization to mitochondrion	ISO	J:164563
Biological Process	GO:0051262	protein tetramerization	ISO	J:280922
Biological Process	GO:1900063	regulation of peroxisome organization	ISO	J:164563
Biological Process	GO:1900063	regulation of peroxisome organization	IMP	J:167950
Biological Process	GO:0039529	RIG-I signaling pathway	IGI	J:186390
Biological Process	GO:0007165	signal transduction	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IMP	J:167950

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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