GO Annotations Graph

• Symbol: Sgms1
• Name: sphingomyelin synthase 1
• ID: MGI:2444110

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047493	ceramide cholinephosphotransferase activity	ISS	J:105120
Molecular Function	GO:0047493	ceramide cholinephosphotransferase activity	ISO	J:164563
Molecular Function	GO:0047493	ceramide cholinephosphotransferase activity	IBA	J:265628
Molecular Function	GO:0002950	ceramide phosphoethanolamine synthase activity	IMP	J:220024
Molecular Function	GO:0002950	ceramide phosphoethanolamine synthase activity	ISO	J:220024
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	IEA	J:72247
Molecular Function	GO:0033188	sphingomyelin synthase activity	IDA	J:292436
Molecular Function	GO:0033188	sphingomyelin synthase activity	ISO	J:164563
Molecular Function	GO:0033188	sphingomyelin synthase activity	IMP	J:122696
Molecular Function	GO:0033188	sphingomyelin synthase activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	TAS	J:122696
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0000139	Golgi membrane	ISS	J:105120
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0000138	Golgi trans cisterna	ISO	J:105120
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	TAS	J:122696
Cellular Component	GO:0005886	plasma membrane	TAS	J:122696
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0046513	ceramide biosynthetic process	IBA	J:265628
Biological Process	GO:0046513	ceramide biosynthetic process	ISO	J:220024
Biological Process	GO:0046513	ceramide biosynthetic process	IMP	J:220024
Biological Process	GO:0006954	inflammatory response	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0006665	sphingolipid metabolic process	IEA	J:60000
Biological Process	GO:0006686	sphingomyelin biosynthetic process	ISS	J:105120
Biological Process	GO:0006686	sphingomyelin biosynthetic process	ISO	J:164563
Biological Process	GO:0006686	sphingomyelin biosynthetic process	IMP	J:292436
Biological Process	GO:0006686	sphingomyelin biosynthetic process	IBA	J:265628