GO Annotations Graph

• Symbol: Vps18
• Name: VPS18 CORVET/HOPS core subunit
• ID: MGI:2443626

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:90042
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:159132
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IBA	J:265628
Molecular Function	GO:0019905	syntaxin binding	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Cellular Component	GO:0005884	actin filament	IDA	J:90042
Cellular Component	GO:0030123	AP-3 adaptor complex	IDA	J:222677
Cellular Component	GO:0033263	CORVET complex	IDA	J:222663
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005769	early endosome	IDA	J:90042
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0030897	HOPS complex	ISO	J:164563
Cellular Component	GO:0030897	HOPS complex	IBA	J:265628
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Biological Process	GO:0006914	autophagy	IEA	J:60000
Biological Process	GO:0007032	endosome organization	ISO	J:164563
Biological Process	GO:0007032	endosome organization	IBA	J:265628
Biological Process	GO:0007032	endosome organization	IDA	J:90042
Biological Process	GO:0008333	endosome to lysosome transport	ISO	J:164563
Biological Process	GO:0008333	endosome to lysosome transport	IBA	J:265628
Biological Process	GO:0006886	intracellular protein transport	IEA	J:72247
Biological Process	GO:0007040	lysosome organization	ISO	J:164563
Biological Process	GO:0007040	lysosome organization	IBA	J:265628
Biological Process	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0048284	organelle fusion	IBA	J:265628
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	ISO	J:164563
Biological Process	GO:0006904	vesicle docking involved in exocytosis	IBA	J:265628
Biological Process	GO:0016192	vesicle-mediated transport	IEA	J:72247
Biological Process	GO:0046718	viral entry into host cell	IMP	J:206800