GO Annotations Graph

• Symbol: Ddx11
• Name: DEAD/H box helicase 11
• ID: MGI:2443590

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0043139	5'-3' DNA helicase activity	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	ISO	J:164563
Molecular Function	GO:0008186	ATP-dependent activity, acting on RNA	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003678	DNA helicase activity	ISO	J:164563
Molecular Function	GO:0003678	DNA helicase activity	IBA	J:265628
Molecular Function	GO:0003688	DNA replication origin binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0051880	G-quadruplex DNA binding	ISO	J:164563
Molecular Function	GO:0004386	helicase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEA	J:72247
Molecular Function	GO:0051536	iron-sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003727	single-stranded RNA binding	ISO	J:164563
Molecular Function	GO:0045142	triplex DNA binding	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0031390	Ctf18 RFC-like complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0032508	DNA duplex unwinding	IBA	J:265628
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0006260	DNA replication	IEA	J:60000
Biological Process	GO:0034085	establishment of sister chromatid cohesion	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0006139	nucleobase-containing compound metabolic process	IEA	J:72247