GO Annotations Graph

• Symbol: Thrap3
• Name: thyroid hormone receptor associated protein 3
• ID: MGI:2442637

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0051219	phosphoprotein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:201135
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:201135
Molecular Function	GO:0003713	transcription coactivator activity	IMP	J:201135
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:73065
Molecular Function	GO:0003712	transcription coregulator activity	ISO	J:164563
Molecular Function	GO:0003712	transcription coregulator activity	IBA	J:265628
Cellular Component	GO:0035145	exon-exon junction complex	ISO	J:164563
Cellular Component	GO:0016592	mediator complex	IBA	J:265628
Cellular Component	GO:0016592	mediator complex	IDA	J:77765
Cellular Component	GO:0016592	mediator complex	ISO	J:73065
Cellular Component	GO:0016592	mediator complex	IDA	J:92973
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-556760
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0007623	circadian rhythm	IEP	J:201135
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0048255	mRNA stabilization	ISO	J:164563
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	ISO	J:164563
Biological Process	GO:0042753	positive regulation of circadian rhythm	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0048026	positive regulation of mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0008380	RNA splicing	IEA	J:60000
Biological Process	GO:0008380	RNA splicing	IEA	J:72247
Biological Process	GO:0006366	transcription by RNA polymerase II	IC	J:77765