GO Annotations Graph

• Symbol: Sh3pxd2b
• Name: SH3 and PX domains 2B
• ID: MGI:2442062

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035091	phosphatidylinositol binding	IEA	J:72247
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	IDA	J:143263
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	IMP	J:143263
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	IDA	J:143263
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	IDA	J:143263
Molecular Function	GO:0042169	SH2 domain binding	IDA	J:143263
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	IBA	J:265628
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:169985
Cellular Component	GO:0005737	cytoplasm	IDA	J:143263
Cellular Component	GO:0005737	cytoplasm	IDA	J:153369
Cellular Component	GO:0005737	cytoplasm	IDA	J:235640
Cellular Component	GO:0002102	podosome	IDA	J:153369
Cellular Component	GO:0002102	podosome	IDA	J:169985
Biological Process	GO:0060612	adipose tissue development	IMP	J:158635
Biological Process	GO:0060348	bone development	ISO	J:164563
Biological Process	GO:0060348	bone development	IMP	J:158635
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:1904888	cranial skeletal system development	IMP	J:235640
Biological Process	GO:0022617	extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:0001654	eye development	IMP	J:158635
Biological Process	GO:0001654	eye development	ISO	J:164563
Biological Process	GO:0007507	heart development	IMP	J:158635
Biological Process	GO:0007507	heart development	ISO	J:164563
Biological Process	GO:0002051	osteoblast fate commitment	IMP	J:235640
Biological Process	GO:0071800	podosome assembly	IMP	J:169985
Biological Process	GO:1904179	positive regulation of adipose tissue development	IMP	J:235640
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IMP	J:143263
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IMP	J:235640
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:235640
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:235640
Biological Process	GO:0051496	positive regulation of stress fiber assembly	IMP	J:235640
Biological Process	GO:0072657	protein localization to membrane	ISO	J:164563
Biological Process	GO:0060378	regulation of brood size	IMP	J:235640
Biological Process	GO:0001501	skeletal system development	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:158635
Biological Process	GO:0048705	skeletal system morphogenesis	IMP	J:235640
Biological Process	GO:0042554	superoxide anion generation	IBA	J:265628
Biological Process	GO:0006801	superoxide metabolic process	ISO	J:164563