GO Annotations Graph

• Symbol: Tox
• Name: thymocyte selection-associated high mobility group box
• ID: MGI:2181659

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:220033
Molecular Function	GO:0031490	chromatin DNA binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IDA	J:74993
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	IMP	J:131287
Biological Process	GO:0002362	CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment	IMP	J:131287
Biological Process	GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	IMP	J:74993
Biological Process	GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	IMP	J:91035
Biological Process	GO:0021895	cerebral cortex neuron differentiation	IMP	J:220033
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0002521	leukocyte differentiation	IBA	J:265628
Biological Process	GO:0048535	lymph node development	IMP	J:164687
Biological Process	GO:0030098	lymphocyte differentiation	IMP	J:164687
Biological Process	GO:0001779	natural killer cell differentiation	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0002364	NK T cell lineage commitment	IMP	J:131287
Biological Process	GO:0048541	Peyer's patch development	IMP	J:164687
Biological Process	GO:1901537	positive regulation of DNA demethylation	IMP	J:91035
Biological Process	GO:0032825	positive regulation of natural killer cell differentiation	IMP	J:164687
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	IMP	J:220033
Biological Process	GO:0010976	positive regulation of neuron projection development	IMP	J:220033
Biological Process	GO:1902232	regulation of positive thymic T cell selection	IMP	J:131287
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628