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GO Annotations Graph
Symbol
Name
ID
Pkhd1
polycystic kidney and hepatic disease 1
MGI:2155808

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005515protein bindingIPIJ:102836
Molecular FunctionGO:0005515protein bindingIPIJ:143394
Molecular FunctionGO:0005515protein bindingIPIJ:246963
Molecular FunctionGO:0005515protein bindingIPIJ:215153
Cellular ComponentGO:00977319+0 non-motile ciliumIDAJ:215153
Cellular ComponentGO:0016324apical plasma membraneISOJ:164563
Cellular ComponentGO:0016324apical plasma membraneIDAJ:131370
Cellular ComponentGO:0042995cell projectionIEAJ:60000
Cellular ComponentGO:0005813centrosomeISOJ:164563
Cellular ComponentGO:0005694chromosomeIEAJ:60000
Cellular ComponentGO:0000775chromosome, centromeric regionIEAJ:60000
Cellular ComponentGO:0036064ciliary basal bodyISOJ:164563
Cellular ComponentGO:0005929ciliumIDAJ:296131
Cellular ComponentGO:0005929ciliumIDAJ:131370
Cellular ComponentGO:0005929ciliumIDAJ:187735
Cellular ComponentGO:0005929ciliumISOJ:155856
Cellular ComponentGO:0005929ciliumISOJ:164563
Cellular ComponentGO:0005929ciliumIDAJ:296158
Cellular ComponentGO:0005929ciliumIDAJ:246963
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0005783endoplasmic reticulumIDAJ:296109
Cellular ComponentGO:0070062extracellular exosomeIDAJ:187735
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005794Golgi apparatusIDAJ:296109
Cellular ComponentGO:0016020membraneISOJ:155856
Cellular ComponentGO:0072686mitotic spindleISOJ:164563
Cellular ComponentGO:0005634nucleusIEAJ:60000
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:164563
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Biological ProcessGO:0048754branching morphogenesis of an epithelial tubeIMPJ:167782
Biological ProcessGO:0045216cell-cell junction organizationIMPJ:167782
Biological ProcessGO:0060271cilium assemblyIMPJ:143394
Biological ProcessGO:0000132establishment of mitotic spindle orientationIMPJ:185863
Biological ProcessGO:0006874intracellular calcium ion homeostasisISOJ:164563
Biological ProcessGO:0001822kidney developmentIDAJ:89193
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:164563
Biological ProcessGO:1904036negative regulation of epithelial cell apoptotic processIMPJ:167782
Biological ProcessGO:0032088negative regulation of NF-kappaB transcription factor activityISOJ:164563
Biological ProcessGO:0051898negative regulation of protein kinase B signalingISOJ:164563
Biological ProcessGO:0008284positive regulation of cell population proliferationISOJ:164563
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationIMPJ:167782
Biological ProcessGO:0010824regulation of centrosome duplicationISOJ:164563
Biological ProcessGO:1904054regulation of cholangiocyte proliferationISOJ:164563
Biological ProcessGO:0070372regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0090175regulation of establishment of planar polarityIMPJ:185863
Biological ProcessGO:0032006regulation of TOR signalingISOJ:164563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory