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GO Annotations Graph
Symbol
Name
ID
Gsk3a
glycogen synthase kinase 3 alpha
MGI:2152453

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:115106
Molecular FunctionGO:0034236protein kinase A catalytic subunit bindingISOJ:164563
Molecular FunctionGO:0034236protein kinase A catalytic subunit bindingISOJ:155856
Molecular FunctionGO:0004672protein kinase activityIDAJ:87871
Molecular FunctionGO:0019901protein kinase bindingISOJ:155856
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0004674protein serine/threonine kinase activityIMPJ:201566
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:155856
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:135361
Molecular FunctionGO:0050321tau-protein kinase activityIEAJ:72245
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005874microtubuleISOJ:155856
Biological ProcessGO:0007568agingISOJ:155856
Biological ProcessGO:0005975carbohydrate metabolic processIEAJ:60000
Biological ProcessGO:0003214cardiac left ventricle morphogenesisIMPJ:163724
Biological ProcessGO:0016477cell migrationIGIJ:135361
Biological ProcessGO:0032869cellular response to insulin stimulusISOJ:164563
Biological ProcessGO:0036016cellular response to interleukin-3IDAJ:201566
Biological ProcessGO:0071285cellular response to lithium ionIDAJ:99298
Biological ProcessGO:0071407cellular response to organic cyclic compoundIDAJ:78619
Biological ProcessGO:0097192extrinsic apoptotic signaling pathway in absence of ligandIDAJ:201566
Biological ProcessGO:0005977glycogen metabolic processIEAJ:60000
Biological ProcessGO:0044027hypermethylation of CpG islandIMPJ:173141
Biological ProcessGO:0008286insulin receptor signaling pathwayIDAJ:145810
Biological ProcessGO:0061052negative regulation of cell growth involved in cardiac muscle cell developmentIMPJ:163724
Biological ProcessGO:2000171negative regulation of dendrite developmentISOJ:155856
Biological ProcessGO:0046325negative regulation of glucose importISOJ:164563
Biological ProcessGO:1904227negative regulation of glycogen synthase activity, transferring glucose-1-phosphateISOJ:164563
Biological ProcessGO:0046627negative regulation of insulin receptor signaling pathwayISOJ:164563
Biological ProcessGO:0009968negative regulation of signal transductionIEAJ:60000
Biological ProcessGO:0032007negative regulation of TOR signalingIMPJ:163724
Biological ProcessGO:0007399nervous system developmentIEAJ:60000
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0071879positive regulation of adrenergic receptor signaling pathwayIMPJ:163724
Biological ProcessGO:0030819positive regulation of cAMP biosynthetic processIMPJ:163724
Biological ProcessGO:2000467positive regulation of glycogen (starch) synthase activityIMPJ:163724
Biological ProcessGO:0045823positive regulation of heart contractionIMPJ:163724
Biological ProcessGO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayIDAJ:201566
Biological ProcessGO:0043525positive regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationIDAJ:135361
Biological ProcessGO:0010800positive regulation of peptidyl-threonine phosphorylationIDAJ:135361
Biological ProcessGO:1903955positive regulation of protein targeting to mitochondrionISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIMPJ:173141
Biological ProcessGO:0043161proteasome-mediated ubiquitin-dependent protein catabolic processIDAJ:201566
Biological ProcessGO:0006468protein phosphorylationIMPJ:201566
Biological ProcessGO:0006468protein phosphorylationIDAJ:87871
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0006468protein phosphorylationISOJ:155856
Biological ProcessGO:0006349regulation of gene expression by genetic imprintingIMPJ:173141
Biological ProcessGO:1903146regulation of mitophagyISOJ:164563
Biological ProcessGO:0003073regulation of systemic arterial blood pressureIMPJ:163724
Biological ProcessGO:0016055Wnt signaling pathwayIEAJ:60000


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory