GO Annotations Graph

• Symbol: Mylk2
• Name: myosin, light polypeptide kinase 2, skeletal muscle
• ID: MGI:2139434

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0032027	myosin light chain binding	ISO	J:155856
Molecular Function	GO:0032027	myosin light chain binding	IBA	J:265628
Molecular Function	GO:0004687	myosin light chain kinase activity	ISO	J:155856
Molecular Function	GO:0004687	myosin light chain kinase activity	ISO	J:164563
Molecular Function	GO:0004687	myosin light chain kinase activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:173154
Molecular Function	GO:0005515	protein binding	IPI	J:144071
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0045202	synapse	IGI	J:109028
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0055007	cardiac muscle cell differentiation	NAS	J:173154
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	ISO	J:164563
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	IBA	J:265628
Biological Process	GO:0007274	neuromuscular synaptic transmission	IGI	J:109028
Biological Process	GO:0007274	neuromuscular synaptic transmission	IMP	J:109028
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:155856
Biological Process	GO:0043408	regulation of MAPK cascade	ISO	J:155856
Biological Process	GO:0006937	regulation of muscle contraction	ISO	J:155856
Biological Process	GO:0032971	regulation of muscle filament sliding	ISO	J:164563
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	ISO	J:155856
Biological Process	GO:0035914	skeletal muscle cell differentiation	NAS	J:173154
Biological Process	GO:0035914	skeletal muscle cell differentiation	ISO	J:164563
Biological Process	GO:0014816	skeletal muscle satellite cell differentiation	IMP	J:173154
Biological Process	GO:0006941	striated muscle contraction	ISO	J:164563
Biological Process	GO:0006941	striated muscle contraction	IBA	J:265628
Biological Process	GO:0048489	synaptic vesicle transport	ISO	J:155856
Biological Process	GO:0006833	water transport	ISO	J:155856