GO Annotations Graph

• Symbol: Rnf111
• Name: ring finger 111
• ID: MGI:1934919

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:152659
Molecular Function	GO:0005515	protein binding	IPI	J:238299
Molecular Function	GO:0005515	protein binding	IPI	J:238299
Molecular Function	GO:0005515	protein binding	IPI	J:109361
Molecular Function	GO:0046332	SMAD binding	ISO	J:155856
Molecular Function	GO:0046332	SMAD binding	IBA	J:265628
Molecular Function	GO:0032184	SUMO polymer binding	ISO	J:164563
Molecular Function	GO:0032184	SUMO polymer binding	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IMP	J:109361
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TAS	Reactome:R-NUL-2186755
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:109361
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-2186736
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-2186755
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-2186775
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:71817
Cellular Component	GO:0005634	nucleus	IDA	J:109361
Cellular Component	GO:0032991	protein-containing complex	IDA	J:109361
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007389	pattern specification process	IMP	J:68833
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:109361
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IMP	J:109361
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IDA	J:109361
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	IBA	J:265628
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	IDA	J:109361
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	IMP	J:109361
Biological Process	GO:0000209	protein polyubiquitination	IMP	J:109361
Biological Process	GO:0000209	protein polyubiquitination	IDA	J:109361
Biological Process	GO:0000209	protein polyubiquitination	IGI	J:109361
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0030579	ubiquitin-dependent SMAD protein catabolic process	IMP	J:109361
Biological Process	GO:0030579	ubiquitin-dependent SMAD protein catabolic process	IBA	J:265628
Biological Process	GO:0030579	ubiquitin-dependent SMAD protein catabolic process	IDA	J:109361