GO Annotations Graph

• Symbol: Akap12
• Name: A kinase anchor protein 12
• ID: MGI:1932576

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008179	adenylate cyclase binding	ISO	J:164563
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0005516	calmodulin binding	IEA	J:72247
Molecular Function	GO:0051018	protein kinase A binding	IEA	J:72247
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	TAS	J:67308
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:192016
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:192016
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IEP	J:192016
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:192016
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IEP	J:192016
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:192016
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:192016
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:192016
Biological Process	GO:0043116	negative regulation of vascular permeability	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0061870	positive regulation of hepatic stellate cell migration	ISO	J:155856
Biological Process	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	ISO	J:155856
Biological Process	GO:1900143	positive regulation of oligodendrocyte apoptotic process	ISO	J:155856
Biological Process	GO:0010739	positive regulation of protein kinase A signaling	IEA	J:72247
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:0010738	regulation of protein kinase A signaling	ISO	J:164563
Biological Process	GO:0010738	regulation of protein kinase A signaling	IBA	J:265628
Biological Process	GO:0090036	regulation of protein kinase C signaling	IEA	J:72247
Biological Process	GO:0007165	signal transduction	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0007165	signal transduction	TAS	J:67308