GO Annotations Graph

• Symbol: Il23a
• Name: interleukin 23, alpha subunit p19
• ID: MGI:1932410

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IEA	J:60000
Molecular Function	GO:0005125	cytokine activity	IEA	J:72247
Molecular Function	GO:0045519	interleukin-23 receptor binding	IPI	J:65966
Molecular Function	GO:0045519	interleukin-23 receptor binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:65966
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8950442
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8950612
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8950679
Cellular Component	GO:0005615	extracellular space	IDA	J:314396
Cellular Component	GO:0005615	extracellular space	IDA	J:168000
Cellular Component	GO:0070743	interleukin-23 complex	ISO	J:164563
Cellular Component	GO:0070743	interleukin-23 complex	IDA	J:65966
Cellular Component	GO:0070743	interleukin-23 complex	IPI	J:65966
Cellular Component	GO:0070743	interleukin-23 complex	ISO	J:164563
Cellular Component	GO:0070743	interleukin-23 complex	IBA	J:265628
Cellular Component	GO:0072536	interleukin-23 receptor complex	NAS	J:76845
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IEA	J:60000
Biological Process	GO:0006955	immune response	NAS	J:319975
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0032693	negative regulation of interleukin-10 production	ISO	J:164563
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	ISO	J:164563
Biological Process	GO:0010536	positive regulation of activation of Janus kinase activity	ISO	J:164563
Biological Process	GO:0010536	positive regulation of activation of Janus kinase activity	IBA	J:265628
Biological Process	GO:0002230	positive regulation of defense response to virus by host	ISO	J:164563
Biological Process	GO:0002230	positive regulation of defense response to virus by host	IDA	J:87643
Biological Process	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	ISO	J:164563
Biological Process	GO:0032733	positive regulation of interleukin-10 production	ISO	J:164563
Biological Process	GO:0032735	positive regulation of interleukin-12 production	ISO	J:164563
Biological Process	GO:0032740	positive regulation of interleukin-17 production	ISO	J:164563
Biological Process	GO:0032740	positive regulation of interleukin-17 production	NAS	J:320271
Biological Process	GO:0043382	positive regulation of memory T cell differentiation	IDA	J:87643
Biological Process	GO:0032819	positive regulation of natural killer cell proliferation	ISO	J:164563
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	IDA	J:147573
Biological Process	GO:0051135	positive regulation of NK T cell activation	ISO	J:164563
Biological Process	GO:0051142	positive regulation of NK T cell proliferation	NAS	J:319975
Biological Process	GO:0051142	positive regulation of NK T cell proliferation	ISO	J:164563
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	ISO	J:164563
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	ISO	J:164563
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	IDA	J:87643
Biological Process	GO:0042102	positive regulation of T cell proliferation	ISO	J:164563
Biological Process	GO:0042102	positive regulation of T cell proliferation	ISO	J:164563
Biological Process	GO:0042102	positive regulation of T cell proliferation	IDA	J:65966
Biological Process	GO:0042102	positive regulation of T cell proliferation	IBA	J:265628
Biological Process	GO:0002827	positive regulation of T-helper 1 type immune response	IDA	J:87643
Biological Process	GO:0002827	positive regulation of T-helper 1 type immune response	ISO	J:164563
Biological Process	GO:2000330	positive regulation of T-helper 17 cell lineage commitment	IDA	J:150655
Biological Process	GO:2000330	positive regulation of T-helper 17 cell lineage commitment	IBA	J:265628
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	NAS	J:320271
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	IDA	J:150655
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:151963
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:151963
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032729	positive regulation of type II interferon production	ISO	J:164563
Biological Process	GO:0032729	positive regulation of type II interferon production	ISO	J:164563
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:0042098	T cell proliferation	IDA	J:124638
Biological Process	GO:0048771	tissue remodeling	IEA	J:60000