GO Annotations Graph

• Symbol: Mlst8
• Name: MTOR associated protein, LST8 homolog (S. cerevisiae)
• ID: MGI:1929514

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0031931	TORC1 complex	ISO	J:164563
Cellular Component	GO:0031931	TORC1 complex	IDA	J:237685
Cellular Component	GO:0031931	TORC1 complex	IBA	J:265628
Cellular Component	GO:0031931	TORC1 complex	ISO	J:93907
Cellular Component	GO:0031932	TORC2 complex	ISO	J:164563
Cellular Component	GO:0031932	TORC2 complex	IBA	J:265628
Cellular Component	GO:0031932	TORC2 complex	ISO	J:93907
Biological Process	GO:0071456	cellular response to hypoxia	NAS	J:320285
Biological Process	GO:0031669	cellular response to nutrient levels	NAS	J:319697
Biological Process	GO:0031669	cellular response to nutrient levels	NAS	J:319972
Biological Process	GO:0071470	cellular response to osmotic stress	NAS	J:320285
Biological Process	GO:0007010	cytoskeleton organization	NAS	J:320275
Biological Process	GO:0006974	DNA damage response	NAS	J:320285
Biological Process	GO:0043066	negative regulation of apoptotic process	NAS	J:319697
Biological Process	GO:0010507	negative regulation of autophagy	NAS	J:320286
Biological Process	GO:0016310	phosphorylation	ISO	J:164563
Biological Process	GO:0030838	positive regulation of actin filament polymerization	IMP	J:93907
Biological Process	GO:0030307	positive regulation of cell growth	NAS	J:319682
Biological Process	GO:0030307	positive regulation of cell growth	NAS	J:319697
Biological Process	GO:0045821	positive regulation of glycolytic process	NAS	J:163259
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	NAS	J:163259
Biological Process	GO:1905857	positive regulation of pentose-phosphate shunt	NAS	J:163259
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IMP	J:93907
Biological Process	GO:0032008	positive regulation of TOR signaling	ISO	J:164563
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	IMP	J:93907
Biological Process	GO:0031929	TOR signaling	IBA	J:265628
Biological Process	GO:0038202	TORC1 signaling	ISO	J:164563