GO Annotations Graph

• Symbol: Gprc5b
• Name: G protein-coupled receptor, family C, group 5, member B
• ID: MGI:1927596

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0030295	protein kinase activator activity	IBA	J:265628
Molecular Function	GO:0030295	protein kinase activator activity	ISO	J:73065
Molecular Function	GO:0019901	protein kinase binding	IPI	J:205618
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0019901	protein kinase binding	ISO	J:73065
Cellular Component	GO:0009986	cell surface	IDA	J:204990
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0070062	extracellular exosome	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	IDA	J:205618
Cellular Component	GO:0045121	membrane raft	ISO	J:73065
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0042593	glucose homeostasis	IMP	J:205618
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IGI	J:205618
Biological Process	GO:0007626	locomotory behavior	IMP	J:176063
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP	J:204990
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:205618
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IGI	J:205618
Biological Process	GO:0050729	positive regulation of inflammatory response	IMP	J:205618
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	IMP	J:205618
Biological Process	GO:0045666	positive regulation of neuron differentiation	IMP	J:204990
Biological Process	GO:0010976	positive regulation of neuron projection development	IDA	J:160131
Biological Process	GO:0045860	positive regulation of protein kinase activity	IMP	J:205618
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IMP	J:205618
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	IMP	J:205618
Biological Process	GO:0006468	protein phosphorylation	IMP	J:205618
Biological Process	GO:0007165	signal transduction	IEA	J:60000