GO Annotations Graph

• Symbol: Herpud1
• Name: homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
• ID: MGI:1927406

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:177751
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	IBA	J:265628
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	IMP	J:177751
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:217284
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:200660
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:65186
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	IDA	J:296102
Cellular Component	GO:1990037	Lewy body core	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:65186
Biological Process	GO:0032469	endoplasmic reticulum calcium ion homeostasis	ISO	J:164563
Biological Process	GO:0032469	endoplasmic reticulum calcium ion homeostasis	IBA	J:265628
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	ISO	J:155856
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IBA	J:265628
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IDA	J:65186
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:155856
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:155856
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0045047	protein targeting to ER	IMP	J:296102
Biological Process	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	IMP	J:217284
Biological Process	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process	IMP	J:217284
Biological Process	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0031396	regulation of protein ubiquitination	IMP	J:177751
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IDA	J:220017
Biological Process	GO:0006986	response to unfolded protein	IEA	J:60000
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	ISO	J:164563
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IDA	J:177751
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IMP	J:177751