GO Annotations Graph

• Symbol: Tnip1
• Name: TNFAIP3 interacting protein 1
• ID: MGI:1926194

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	ISO	J:164563
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	IBA	J:265628
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	IDA	J:183962
Molecular Function	GO:0005515	protein binding	IPI	J:180054
Molecular Function	GO:0005515	protein binding	IPI	J:145539
Molecular Function	GO:0005515	protein binding	IPI	J:186074
Molecular Function	GO:0005515	protein binding	IPI	J:64942
Cellular Component	GO:0005737	cytoplasm	IDA	J:64942
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IBA	J:265628
Biological Process	GO:0009101	glycoprotein biosynthetic process	ISO	J:164563
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0007159	leukocyte cell-cell adhesion	ISO	J:164563
Biological Process	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	IDA	J:180054
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	IBA	J:265628
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	IDA	J:183962
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:0050729	positive regulation of inflammatory response	IMP	J:180054
Biological Process	GO:1903003	positive regulation of protein deubiquitination	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:180054
Biological Process	GO:0050727	regulation of inflammatory response	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628