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GO Annotations Graph
Symbol
Name
ID
Smurf1
SMAD specific E3 ubiquitin protein ligase 1
MGI:1923038

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0043773coenzyme F420-0 gamma-glutamyl ligase activityIEAJ:72245
Molecular FunctionGO:0043774coenzyme F420-2 alpha-glutamyl ligase activityIEAJ:72245
Molecular FunctionGO:0070411I-SMAD bindingISOJ:164563
Molecular FunctionGO:0016874ligase activityIEAJ:60000
Molecular FunctionGO:0070739protein-glutamic acid ligase activityIEAJ:72245
Molecular FunctionGO:0070735protein-glycine ligase activityIEAJ:72245
Molecular FunctionGO:0070737protein-glycine ligase activity, elongatingIEAJ:72245
Molecular FunctionGO:0070736protein-glycine ligase activity, initiatingIEAJ:72245
Molecular FunctionGO:0070412R-SMAD bindingISOJ:164563
Molecular FunctionGO:0018169ribosomal S6-glutamic acid ligase activityIEAJ:72245
Molecular FunctionGO:0070740tubulin-glutamic acid ligase activityIEAJ:72245
Molecular FunctionGO:0070738tubulin-glycine ligase activityIEAJ:72245
Molecular FunctionGO:0061630ubiquitin protein ligase activityISOJ:164563
Molecular FunctionGO:0004842ubiquitin-protein transferase activityISOJ:164563
Molecular FunctionGO:0004842ubiquitin-protein transferase activityIBAJ:161428
Molecular FunctionGO:0004842ubiquitin-protein transferase activityISSJ:114795
Molecular FunctionGO:0008766UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activityIEAJ:72245
Cellular ComponentGO:0030424axonISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005739colocalizes_with
mitochondrion
ISOJ:164563
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0030509BMP signaling pathwayISOJ:164563
Biological ProcessGO:0030154cell differentiationISOJ:164563
Biological ProcessGO:0030154cell differentiationISSJ:114795
Biological ProcessGO:0061736engulfment of target by autophagosomeISOJ:164563
Biological ProcessGO:0098779mitophagy in response to mitochondrial depolarizationISOJ:164563
Biological ProcessGO:0098779mitophagy in response to mitochondrial depolarizationIMPJ:178302
Biological ProcessGO:0030279negative regulation of ossificationIMPJ:97303
Biological ProcessGO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayISOJ:164563
Biological ProcessGO:0002230positive regulation of defense response to virus by hostISOJ:164563
Biological ProcessGO:1903861positive regulation of dendrite extensionISOJ:164563
Biological ProcessGO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processISOJ:164563
Biological ProcessGO:0043161proteasome-mediated ubiquitin-dependent protein catabolic processISOJ:164563
Biological ProcessGO:0006611protein export from nucleusISOJ:164563
Biological ProcessGO:0034394protein localization to cell surfaceISOJ:164563
Biological ProcessGO:0000209protein polyubiquitinationISOJ:164563
Biological ProcessGO:0071211protein targeting to vacuole involved in autophagyISOJ:164563
Biological ProcessGO:0016567protein ubiquitinationISOJ:164563
Biological ProcessGO:0016567protein ubiquitinationIMPJ:97303
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processIBAJ:161428
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processISSJ:114795
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processISOJ:164563
Biological ProcessGO:0032801receptor catabolic processISOJ:164563
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayIBAJ:161428
Biological ProcessGO:0030579ubiquitin-dependent SMAD protein catabolic processISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/21/2020
MGI 6.14
The Jackson Laboratory