GO Annotations Graph

• Symbol: Syvn1
• Name: synovial apoptosis inhibitor 1, synoviolin
• ID: MGI:1921376

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051117	ATPase binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:178646
Molecular Function	GO:0005515	protein binding	IPI	J:270663
Molecular Function	GO:0005515	protein binding	IPI	J:215786
Molecular Function	GO:0005515	protein binding	IPI	J:200386
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IMP	J:270663
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:178646
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:80665
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:73065
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:73065
Molecular Function	GO:1990381	ubiquitin-specific protease binding	ISO	J:164563
Molecular Function	GO:0051082	unfolded protein binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0036513	Derlin-1 retrotranslocation complex	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:80665
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	IDA	J:296095
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	ISO	J:164563
Cellular Component	GO:0000836	Hrd1p ubiquitin ligase complex	IEA	J:72247
Cellular Component	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005790	smooth endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0000151	ubiquitin ligase complex	ISO	J:80665
Biological Process	GO:0036503	ERAD pathway	IDA	J:222676
Biological Process	GO:0036503	ERAD pathway	ISO	J:164563
Biological Process	GO:0002327	immature B cell differentiation	IMP	J:270663
Biological Process	GO:0001701	in utero embryonic development	IMP	J:97254
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:97254
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:97254
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	IMP	J:97254
Biological Process	GO:0030163	protein catabolic process	IMP	J:172947
Biological Process	GO:0070936	protein K48-linked ubiquitination	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	IDA	J:222676
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0006986	response to unfolded protein	ISO	J:80665
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	ISO	J:164563
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	ISO	J:73065
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IDA	J:178646