GO Annotations Graph

• Symbol: Vsir
• Name: V-set immunoregulatory receptor
• ID: MGI:1921298

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0061133	endopeptidase activator activity	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:192401
Molecular Function	GO:0005515	protein binding	IPI	J:193667
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:179154
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:179154
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:179154
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:176836
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:193667
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:179154
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:176836
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:193667
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:193667
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:192401
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:193667
Biological Process	GO:0046636	negative regulation of alpha-beta T cell activation	IBA	J:265628
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	ISO	J:164563
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	IDA	J:176836
Biological Process	GO:2000565	negative regulation of CD8-positive, alpha-beta T cell proliferation	ISO	J:164563
Biological Process	GO:0032693	negative regulation of interleukin-10 production	ISO	J:164563
Biological Process	GO:0032700	negative regulation of interleukin-17 production	ISO	J:164563
Biological Process	GO:0002725	negative regulation of T cell cytokine production	IDA	J:176836
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0032689	negative regulation of type II interferon production	ISO	J:164563
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	IMP	J:193667
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	IGI	J:193667
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0120158	positive regulation of collagen catabolic process	ISO	J:164563
Biological Process	GO:0010950	positive regulation of endopeptidase activity	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	ISO	J:164563
Biological Process	GO:2000738	positive regulation of stem cell differentiation	IGI	J:192401
Biological Process	GO:0050776	regulation of immune response	IEA	J:72247
Biological Process	GO:0048863	stem cell differentiation	IGI	J:192401
Biological Process	GO:0048863	stem cell differentiation	IMP	J:193667
Biological Process	GO:0031638	zymogen activation	ISO	J:164563