GO Annotations Graph

• Symbol: Dlg5
• Name: discs large MAGUK scaffold protein 5
• ID: MGI:1918478

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:73065
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:218232
Molecular Function	GO:0005515	protein binding	IPI	J:238700
Molecular Function	GO:0005515	protein binding	IPI	J:216499
Molecular Function	GO:0005515	protein binding	IPI	J:124940
Cellular Component	GO:0005912	adherens junction	IDA	J:124940
Cellular Component	GO:0005912	adherens junction	IDA	J:94763
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0036064	ciliary basal body	IDA	J:218232
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:216499
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:216499
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:216499
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:216499
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:216499
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:216499
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0014069	postsynaptic density	IDA	J:216499
Cellular Component	GO:0014069	postsynaptic density	IEP	J:216499
Cellular Component	GO:0014069	postsynaptic density	IDA	J:216499
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0045176	apical protein localization	IMP	J:196288
Biological Process	GO:0001837	epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	IMP	J:196288
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IMP	J:196288
Biological Process	GO:0030011	maintenance of cell polarity	ISO	J:164563
Biological Process	GO:0072205	metanephric collecting duct development	IMP	J:124940
Biological Process	GO:0030901	midbrain development	IMP	J:124940
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0035331	negative regulation of hippo signaling	ISO	J:164563
Biological Process	GO:0035331	negative regulation of hippo signaling	IMP	J:238700
Biological Process	GO:0035331	negative regulation of hippo signaling	IBA	J:265628
Biological Process	GO:0042130	negative regulation of T cell proliferation	ISO	J:164563
Biological Process	GO:0060563	neuroepithelial cell differentiation	IMP	J:124940
Biological Process	GO:0030859	polarized epithelial cell differentiation	IMP	J:124940
Biological Process	GO:0030859	polarized epithelial cell differentiation	IMP	J:124940
Biological Process	GO:0060999	positive regulation of dendritic spine development	IMP	J:216499
Biological Process	GO:0035332	positive regulation of hippo signaling	ISO	J:164563
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IMP	J:218232
Biological Process	GO:0051965	positive regulation of synapse assembly	IMP	J:216499
Biological Process	GO:0099173	postsynapse organization	IDA	J:216499
Biological Process	GO:0099173	postsynapse organization	IMP	J:216499
Biological Process	GO:0099173	postsynapse organization	IDA	J:216499
Biological Process	GO:0071896	protein localization to adherens junction	IMP	J:124940
Biological Process	GO:0071896	protein localization to adherens junction	IMP	J:124940
Biological Process	GO:0065003	protein-containing complex assembly	IMP	J:124940
Biological Process	GO:0065003	protein-containing complex assembly	IMP	J:124940
Biological Process	GO:0042981	regulation of apoptotic process	IEA	J:72247
Biological Process	GO:0045186	zonula adherens assembly	IMP	J:124940