GO Annotations Graph

• Symbol: Atp6ap2
• Name: ATPase, H+ transporting, lysosomal accessory protein 2
• ID: MGI:1917745

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0044297	cell body	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0010008	endosome membrane	IDA	J:296116
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:296116
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0045211	postsynaptic membrane	IEA	J:60000
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	ISO	J:164563
Biological Process	GO:0002003	angiotensin maturation	ISO	J:164563
Biological Process	GO:0021626	central nervous system maturation	ISO	J:164563
Biological Process	GO:0021626	central nervous system maturation	IMP	J:296116
Biological Process	GO:0048069	eye pigmentation	ISO	J:164563
Biological Process	GO:0060323	head morphogenesis	ISO	J:164563
Biological Process	GO:0007042	lysosomal lumen acidification	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0032914	positive regulation of transforming growth factor beta1 production	ISO	J:164563
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	IMP	J:156674
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0043408	regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0021903	rostrocaudal neural tube patterning	ISO	J:164563
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	EXP	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IMP	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:326652