GO Annotations Graph

• Symbol: Stx8
• Name: syntaxin 8
• ID: MGI:1890156

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019869	chloride channel inhibitor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:306593
Molecular Function	GO:0005484	SNAP receptor activity	IBA	J:265628
Molecular Function	GO:0000149	SNARE binding	IBA	J:265628
Molecular Function	GO:0000149	SNARE binding	ISO	J:206800
Molecular Function	GO:0019905	syntaxin binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:163442
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0012505	endomembrane system	IBA	J:265628
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:143718
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0031201	SNARE complex	ISO	J:155856
Cellular Component	GO:0031201	SNARE complex	IBA	J:265628
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:143718
Biological Process	GO:0045022	early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:0008333	endosome to lysosome transport	ISO	J:155856
Biological Process	GO:0006886	intracellular protein transport	IBA	J:265628
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0048278	vesicle docking	IBA	J:265628
Biological Process	GO:0006906	vesicle fusion	ISO	J:155856
Biological Process	GO:0006906	vesicle fusion	IBA	J:265628
Biological Process	GO:0016192	vesicle-mediated transport	ISO	J:155856