GO Annotations Graph

• Symbol: Adar
• Name: adenosine deaminase, RNA-specific
• ID: MGI:1889575

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004000	adenosine deaminase activity	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003726	double-stranded RNA adenosine deaminase activity	IBA	J:265628
Molecular Function	GO:0003726	double-stranded RNA adenosine deaminase activity	ISO	J:73065
Molecular Function	GO:0003725	double-stranded RNA binding	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0003692	left-handed Z-DNA binding	TAS	J:74605
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:243505
Molecular Function	GO:0005515	protein binding	IPI	J:189981
Molecular Function	GO:0005515	protein binding	IPI	J:182876
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0008251	tRNA-specific adenosine deaminase activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:87714
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0016607	nuclear speck	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	IDA	J:87714
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:87714
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0044530	supraspliceosomal complex	ISO	J:164563
Biological Process	GO:0006382	adenosine to inosine editing	ISO	J:164563
Biological Process	GO:0006382	adenosine to inosine editing	IDA	J:189989
Biological Process	GO:0006382	adenosine to inosine editing	IBA	J:265628
Biological Process	GO:0006382	adenosine to inosine editing	IMP	J:87715
Biological Process	GO:0006915	apoptotic process	IMP	J:87714
Biological Process	GO:0016553	base conversion or substitution editing	ISO	J:73065
Biological Process	GO:0098586	cellular response to virus	IDA	J:222665
Biological Process	GO:0060216	definitive hemopoiesis	IMP	J:87715
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:65981
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IMP	J:153698
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	IMP	J:142338
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	IMP	J:142338
Biological Process	GO:0097284	hepatocyte apoptotic process	IMP	J:87714
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0035196	miRNA processing	IMP	J:197985
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:1903944	negative regulation of hepatocyte apoptotic process	IMP	J:87714
Biological Process	GO:1900369	negative regulation of post-transcriptional gene silencing by RNA	IMP	J:96920
Biological Process	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation	IMP	J:189981
Biological Process	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	IMP	J:142338
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:192270
Biological Process	GO:0045070	positive regulation of viral genome replication	IMP	J:189981
Biological Process	GO:0045070	positive regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0031054	pre-miRNA processing	ISO	J:73065
Biological Process	GO:0006611	protein export from nucleus	ISO	J:164563
Biological Process	GO:0006606	protein import into nucleus	ISO	J:164563
Biological Process	GO:0035455	response to interferon-alpha	ISO	J:164563
Biological Process	GO:0009615	response to virus	ISO	J:164563
Biological Process	GO:0070922	RISC complex assembly	ISO	J:197985
Biological Process	GO:0006396	RNA processing	IBA	J:265628
Biological Process	GO:0031047	RNA-mediated gene silencing	IEA	J:60000
Biological Process	GO:0002566	somatic diversification of immune receptors via somatic mutation	IDA	J:193867