GO Annotations Graph

• Symbol: Ramp2
• Name: receptor (calcitonin) activity modifying protein 2
• ID: MGI:1859650

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1990409	adrenomedullin binding	ISO	J:164563
Molecular Function	GO:0001605	adrenomedullin receptor activity	ISO	J:164563
Molecular Function	GO:0097643	amylin receptor activity	ISO	J:164563
Molecular Function	GO:0015026	coreceptor activity	ISO	J:155856
Molecular Function	GO:0015026	coreceptor activity	IBA	J:265628
Molecular Function	GO:0015026	coreceptor activity	IDA	J:62792
Cellular Component	GO:1903143	adrenomedullin receptor complex	ISO	J:164563
Cellular Component	GO:0150057	amylin receptor complex 2	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0034333	adherens junction assembly	IMP	J:130931
Biological Process	GO:0034333	adherens junction assembly	ISO	J:164563
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0097647	amylin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IBA	J:265628
Biological Process	GO:0070831	basement membrane assembly	IMP	J:130931
Biological Process	GO:0070830	bicellular tight junction assembly	IMP	J:130931
Biological Process	GO:0070830	bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	IBA	J:265628
Biological Process	GO:0032870	cellular response to hormone stimulus	IBA	J:265628
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	IMP	J:130931
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IPI	J:62792
Biological Process	GO:0007507	heart development	IMP	J:130931
Biological Process	GO:0006886	intracellular protein transport	IEA	J:72247
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	IMP	J:130931
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:0043116	negative regulation of vascular permeability	ISO	J:164563
Biological Process	GO:0043116	negative regulation of vascular permeability	IMP	J:130931
Biological Process	GO:0045766	positive regulation of angiogenesis	IMP	J:130931
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:130931
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:155856
Biological Process	GO:2001214	positive regulation of vasculogenesis	IMP	J:130931
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IBA	J:265628
Biological Process	GO:0015031	protein transport	ISO	J:164563
Biological Process	GO:0015031	protein transport	IBA	J:265628
Biological Process	GO:0031623	receptor internalization	ISO	J:164563
Biological Process	GO:0031623	receptor internalization	ISO	J:155856
Biological Process	GO:0031623	receptor internalization	IBA	J:265628
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:130931
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0002040	sprouting angiogenesis	IMP	J:130931
Biological Process	GO:0097084	vascular associated smooth muscle cell development	IMP	J:130931
Biological Process	GO:0001570	vasculogenesis	ISO	J:164563